Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis

CD47 is a prominent new target in cancer immunotherapy, with antagonistic antibodies currently being evaluated in clinical trials. For effective evaluation of this strategy it is crucial to identify which patients are suited for CD47-targeted therapy. In this respect, expression of the pro-phagocyti...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: He, Yuan, Bouwstra, Renee, Wiersma, Valerie R., de Jong, Mathilde, Jan Lourens, Harm, Fehrmann, Rudolf, de Bruyn, Marco, Ammatuna, Emanuele, Huls, Gerwin, van Meerten, Tom, Bremer, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358615/
https://ncbi.nlm.nih.gov/pubmed/30710089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08013-z
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