Approach to evaluating tumor mutational burden in routine clinical practice

Autor Truesdell, John, Miller, Vincent A., Fabrizio, David
Vydáno v Transl Lung Cancer Res (2018)

Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies

Autor Hartmaier, Ryan J., Charo, Jehad, Fabrizio, David, Goldberg, Michael E., Albacker, Lee A., Pao, William, Chmielecki, Juliann
Vydáno v Genome Med (2017)

EAPH-06. HYPERMUTANT PEDIATRIC HIGH GRADE GLIOMAS ARE DRIVEN BY RAS/MAPK MUTATIONS AND RESPOND TO MEK INHIBITION

Autor Campbell, Brittany B, Morgenstern, Daniel A, Lipman, Tatiana, Fabrizio, David, Shlien, Adam, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri
Vydáno v Neuro Oncol (2018)

A Novel gp41-Binding Adnectin with Potent Anti-HIV Activity Is Highly Synergistic when Linked to a CD4-Binding Adnectin

Autor Wensel, David, Sun, Yongnian, Davis, Jonathan, Li, Zhufang, Zhang, Sharon, McDonagh, Thomas, Fabrizio, David, Cockett, Mark, Krystal, Mark
Vydáno v J Virol (2018)

Evidence‐Based Development and Clinical Use of Precision Oncology Therapeutics

Autor Comment, Leah A., Ward, Ashley F., Schrock, Alexa B., Fabrizio, David, Venstrom, Jeffrey M., Hegde, Priti S., Alexander, Brian M.
Vydáno v Clin Pharmacol Ther (2020)

Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity

Autor Wensel, David, Sun, Yongnian, Li, Zhufang, Zhang, Sharon, Picarillo, Caryn, McDonagh, Thomas, Fabrizio, David, Cockett, Mark, Krystal, Mark, Davis, Jonathan
Vydáno v Antimicrob Agents Chemother (2017)

Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current Evidence

Autor Klempner, Samuel J., Fabrizio, David, Bane, Shalmali, Reinhart, Marcia, Peoples, Tim, Ali, Siraj M., Sokol, Ethan S., Frampton, Garrett, Schrock, Alexa B., Anhorn, Rachel, Reddy, Prasanth
Vydáno v Oncologist (2019)

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma

Autor Ang, Celina, Klempner, Samuel J., Ali, Siraj M., Madison, Russell, Ross, Jeffrey S., Severson, Eric A., Fabrizio, David, Goodman, Aaron, Kurzrock, Razelle, Suh, James, Millis, Sherri Z.
Vydáno v Oncotarget (2019)

Circulating Tumor DNA Identifies EGFR Co-Amplification as a Mechanism of Resistance to Crizotinib in a Patient with Advanced MET-Amplified Lung Adenocarcinoma

Autor Dagogo-Jack, Ibiayi, Fabrizio, David, Lennerz, Jochen, Schrock, Alexa B., Young, Lauren, Mino-Kenudson, Man, Digumarthy, Subba R., Heist, Rebecca S., Ali, Siraj M., Miller, Vincent A., Shaw, Alice T.
Vydáno v J Thorac Oncol (2017)

Prevalence of PDL1 Amplification and Preliminary Response to Immune Checkpoint Blockade in Solid Tumors

Autor Goodman, Aaron M., Piccioni, David, Kato, Shumei, Boichard, Amélie, Wang, Huan-You, Frampton, Garrett, Lippman, Scott M., Connelly, Caitlin, Fabrizio, David, Miller, Vincent, Sicklick, Jason K., Kurzrock, Razelle
Vydáno v JAMA Oncol (2018)

Prevalence of High Tumor Mutational Burden and Association With Survival in Patients With Less Common Solid Tumors

Autor Shao, Changxia, Li, Gerald, Huang, Lingkang, Pruitt, Scott, Castellanos, Emily, Frampton, Garrett, Carson, Kenneth R., Snow, Tamara, Singal, Gaurav, Fabrizio, David, Alexander, Brian M., Jin, Fan, Zhou, Wei
Vydáno v JAMA Netw Open (2020)

DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties

Autor Samad, Tarek A., Srinivasan, Ashok, Karchewski, Laurie A., Jeong, Sung-Jin, Campagna, Jason A., Ji, Ru-Rong, Fabrizio, David A., Zhang, Ying, Lin, Herbert Y., Bell, Esther, Woolf, Clifford J.
Vydáno v J Neurosci (2004)

High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers

Autor Riviere, Paul, Goodman, Aaron M, Okamura, Ryosuke, Barkauskas, Donald A., Whitchurch, Theresa J, Lee, Suzanna, Khalid, Noor, Collier, Rachel, Mareboina, Manvita, Frampton, Garrett M., Fabrizio, David, Sharabi, Andrew B., Kato, Shumei, Kurzrock, Razelle
Vydáno v Mol Cancer Ther (2020)

BRAF internal deletions and resistance to BRAF/MEK inhibitor therapy

Autor Johnson, Douglas B., Childress, Merrida A., Chalmers, Zachary R., Frampton, Garrett M., Ali, Siraj M., Rubinstein, Samuel M., Fabrizio, David, Ross, Jeffrey S., Balasubramanian, Sohail, Miller, Vincent A., Stephens, Philip J., Sosman, Jeffrey A., Lovly, Christine M.
Vydáno v Pigment Cell Melanoma Res (2017)

Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden

Autor Liang, Winnie S., Vergilio, Jo‐Anne, Salhia, Bodour, Huang, Helen J., Oki, Yasuhiro, Garrido‐Laguna, Ignacio, Park, Haeseong, Westin, Jason R., Meric‐Bernstam, Funda, Fabrizio, David, Miller, Vincent A., Stephens, Philip J., Fanale, Michelle A., Ross, Jeffrey S., Janku, Filip
Vydáno v Oncologist (2018)

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3

Autor Ross, Jeffrey S., Fakih, Marwan, Ali, Siraj M., Elvin, Julia A., Schrock, Alexa B., Suh, James, Vergilio, Jo‐Anne, Ramkissoon, Shakti, Severson, Eric, Daniel, Sugganth, Fabrizio, David, Frampton, Garrett, Sun, James, Miller, Vincent A., Stephens, Philip J., Gay, Laurie M.
Vydáno v Cancer (2018)

IMMU-13. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT...

Autor Campbell, Brittany B., Angelini, Paola, Fabrizio, David, Elvin, Julia, Light, Nicholas, Bouffet, Eric, Larouche, Valerie, Samuel, David, Stearns, Duncan, Cole, Kristina, Opocher, Enrico, Thomas, Gregory, Sabel, Magnus, George, Ben, Ziegler, David, Lapierre, Norman, Mason, Gary, Magimajrajan, Vanan, Shlien, Adam, Tabori, Uri
Vydáno v Neuro Oncol (2017)

Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition

Autor Fabrizio, David A., George, Thomas J., Dunne, Richard F., Frampton, Garrett, Sun, James, Gowen, Kyle, Kennedy, Mark, Greenbowe, Joel, Schrock, Alexa B., Hezel, Aram F., Ross, Jeffrey S., Stephens, Phillip J., Ali, Siraj M., Miller, Vincent A., Fakih, Marwan, Klempner, Samuel J.
Vydáno v J Gastrointest Oncol (2018)

HGG-17. TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE REPLICATION REPAIR DEFICIENCY AND PREDICT RESPONSE TO IMMUNE CHECKPOINT INHIBIT...

Autor Campbell, Brittany B, Light, Nicholas, Fabrizio, David, Bouffet, Eric, Larouche, Valerie, Samuel, David, Stearns, Duncan, Cole, Kristina A, Opocher, Enrico, Thomas, Gregory, Sabel, Magnus, Dirks, Peter, Taylor, Michael, Malkin, David, Albrecht, Steffen, Dudley, Roy, Jabado, Nada, Hawkins, Cynthia, Shlien, Adam, Tabori, Uri
Vydáno v Neuro Oncol (2018)

A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient S...

Autor Trabucco, Sally E., Gowen, Kyle, Maund, Sophia L., Sanford, Eric, Fabrizio, David A., Hall, Michael J., Yakirevich, Evgeny, Gregg, Jeffrey P., Stephens, Phil J., Frampton, Garrett M., Hegde, Priti S., Miller, Vincent A., Ross, Jeffrey S., Hartmaier, Ryan J., Huang, Shih-Min A., Sun, James X.
Vydáno v J Mol Diagn (2019)