High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers

Higher tumor mutational burden (TMB) has been correlated with response to checkpoint blockade immunotherapy. However, it is unclear whether TMB independently serves as a prognostic biomarker for outcomes in immunotherapy-naïve patients. Here we evaluated the relationship between TMB and overall surv...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Riviere, Paul, Goodman, Aaron M, Okamura, Ryosuke, Barkauskas, Donald A., Whitchurch, Theresa J, Lee, Suzanna, Khalid, Noor, Collier, Rachel, Mareboina, Manvita, Frampton, Garrett M., Fabrizio, David, Sharabi, Andrew B., Kato, Shumei, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541603/
https://ncbi.nlm.nih.gov/pubmed/32747422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0161
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