Tumor mutational burden is not predictive of cytotoxic chemotherapy response

BACKGROUND: High tumor mutational burden (TMB) predicts checkpoint blockade responsiveness, although the association with outcomes may be nuanced in certain tissue contexts. The correlation between TMB and cytotoxic chemotherapy sensitivity is unknown. This study evaluated the relationship between T...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Nikanjam, Mina, Riviere, Paul, Goodman, Aaron, Barkauskas, Donald A., Frampton, Garrett, Kurzrock, Razelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458654/
https://ncbi.nlm.nih.gov/pubmed/32923144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1781997
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