Tumor mutational burden is not predictive of cytotoxic chemotherapy response

BACKGROUND: High tumor mutational burden (TMB) predicts checkpoint blockade responsiveness, although the association with outcomes may be nuanced in certain tissue contexts. The correlation between TMB and cytotoxic chemotherapy sensitivity is unknown. This study evaluated the relationship between T...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Nikanjam, Mina, Riviere, Paul, Goodman, Aaron, Barkauskas, Donald A., Frampton, Garrett, Kurzrock, Razelle
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458654/
https://ncbi.nlm.nih.gov/pubmed/32923144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1781997
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