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Approach to evaluating tumor mutational burden in routine clinical practice

Immune checkpoint inhibition with monoclonal antibodies has emerged as a promising therapeutic approach but in most tumor types responses are unpredictable and observed in a minority of treated patients. Positive and negative predictive biomarkers for efficacy of these costly drugs are desperately n...

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Bibliografiske detaljer
Udgivet i:Transl Lung Cancer Res
Main Authors: Truesdell, John, Miller, Vincent A., Fabrizio, David
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249621/
https://ncbi.nlm.nih.gov/pubmed/30505712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2018.10.10
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