Cardiotoxicity of the new cancer therapeutics- mechanisms of, and approaches to, the problem

Por Force, Thomas, Kerkelä, Risto
Publicado em 2008

Focusing the spotlight on GSK-3 in aging

Por Zhou, Jibin, Force, Thomas
Publicado em 2013

Mechanism-Based Engineering against Anthracycline Cardiotoxicity

Por Force, Thomas, Wang, Yibin
Publicado em 2013

Protein kinase cascades in the regulation of cardiac hypertrophy

Por Dorn, Gerald W., Force, Thomas
Publicado em 2005

Unique and Overlapping Functions of GSK-3 Isoforms in Cell Differentiation and Proliferation and Cardiovascular Development

Por Force, Thomas, Woodgett, James R.
Publicado em 2009

Mechanisms of cardiomyopathy associated with tyrosine kinase inhibitor cancer therapeutics

Por Chen, Ming Hui, Kerkela, Risto, Force, Thomas
Publicado em 2008

Developing small molecules to inhibit kinases unkind to the heart: p38 MAPK as a case in point

Por Marber, Michael S, Molkentin, Jeffery D., Force, Thomas
Publicado em 2010

Mitogen-Activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-Breaking Tale

Por ROSE, BETH A., FORCE, THOMAS, WANG, YIBIN
Publicado em 2010

Targeting GSK-3 family members in the heart: A very sharp double-edged sword

Por Cheng, Hui, Woodgett, James, Maamari, Mia, Force, Thomas
Publicado em 2010

TNNI3K, a novel cardiac-specific kinase, emerging as a molecular target for the treatment of cardiac disease

Por Lal, Hind, Ahmad, Firdos, Parikh, Shan, Force, Thomas
Publicado em 2014

The GSK-3 family as therapeutic target for myocardial diseases

Por Lal, Hind, Ahmad, Firdos, Woodgett, James, Force, Thomas
Publicado no Circ Res (2015)

Response by Zhou et al to Letter Regarding Article, “Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy”

Por Zhou, Jibin, Ahmad, Firdos, Lal, Hind, Force, Thomas
Publicado no Circ Res (2016)

Gene 33/RALT Is Induced by Hypoxia in Cardiomyocytes, Where It Promotes Cell Death by Suppressing Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Survival S...

Por Xu, Dazhong, Patten, Richard D., Force, Thomas, Kyriakis, John M.
Publicado em 2006

Helix-Loop-Helix Protein p8, a Transcriptional Regulator Required for Cardiomyocyte Hypertrophy and Cardiac Fibroblast Matrix Metalloprotease Induction

Por Goruppi, Sandro, Patten, Richard D., Force, Thomas, Kyriakis, John M.
Publicado em 2007

HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK

Por Volloch, Vladimir, Gabai, Vladimir L., Rits, Sophia, Force, Thomas, Sherman, Michael Y.
Publicado em 2000

Emerging Paradigms in Cardiomyopathies Associated with Cancer Therapies

Por Ky, Bonnie, Vejpongsa, Pimprapa, Yeh, Edward T.H., Force, Thomas, Moslehi, Javid
Publicado em 2013

Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease

Por Vagnozzi, Ronald J., Hoffman, Nicholas E., Elrod, John W., Madesh, Muniswamy, Force, Thomas
Publicado em 2014

A novel pre-clinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity

Por Cheng, Hui, Kari, Gabor, Dicker, Adam P, Rodeck, Ulrich, Koch, Walter J, Force, Thomas
Publicado em 2011

Group IVA Cytosolic Phospholipase A(2) Regulates the G(2)-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2

Por Movahedi Naini, Said, Sheridan, Alice M., Force, Thomas, Shah, Jagesh V., Bonventre, Joseph V.
Publicado no Mol Cell Biol (2015)

SOK1 Translocates from the Golgi to the Nucleus upon Chemical Anoxia and Induces Apoptotic Cell Death

Por Nogueira, Emilio, Fidalgo, Miguel, Molnar, Arpad, Kyriakis, John, Force, Thomas, Zalvide, Juan, Pombo, Celia M.
Publicado em 2008