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Gene 33/RALT Is Induced by Hypoxia in Cardiomyocytes, Where It Promotes Cell Death by Suppressing Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Survival Signaling
Ischemia in the heart deprives cardiomyocytes of oxygen, triggering cell death (myocardial infarction). Ischemia and its cell culture model, hypoxia, elicit a stress response program that contributes to cardiomyocyte death; however, the molecular components required to promote this process remain ne...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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American Society for Microbiology
2006
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489166/ https://ncbi.nlm.nih.gov/pubmed/16782890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02387-05 |
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