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Gene 33/RALT Is Induced by Hypoxia in Cardiomyocytes, Where It Promotes Cell Death by Suppressing Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Survival Signaling

Ischemia in the heart deprives cardiomyocytes of oxygen, triggering cell death (myocardial infarction). Ischemia and its cell culture model, hypoxia, elicit a stress response program that contributes to cardiomyocyte death; however, the molecular components required to promote this process remain ne...

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Detalles Bibliográficos
Main Authors: Xu, Dazhong, Patten, Richard D., Force, Thomas, Kyriakis, John M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489166/
https://ncbi.nlm.nih.gov/pubmed/16782890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02387-05
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