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HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK

The major heat shock protein Hsp72 prevents heat-induced apoptosis. We have previously demonstrated that transiently expressed Hsp72 exerts its anti-apoptotic effect by suppressing the activity of stress-kinase JNK, an early component of the apoptotic pathway initiated by heat shock. On the other ha...

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Autors principals: Volloch, Vladimir, Gabai, Vladimir L., Rits, Sophia, Force, Thomas, Sherman, Michael Y.
Format: Artigo
Idioma:Inglês
Publicat: Cell Stress Society International 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC312900/
https://ncbi.nlm.nih.gov/pubmed/11147965
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