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HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK

The major heat shock protein Hsp72 prevents heat-induced apoptosis. We have previously demonstrated that transiently expressed Hsp72 exerts its anti-apoptotic effect by suppressing the activity of stress-kinase JNK, an early component of the apoptotic pathway initiated by heat shock. On the other ha...

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Udgivet i:Cell Stress Chaperones
Principais autores: Volloch, Vladimir, Gabai, Vladimir L., Rits, Sophia, Force, Thomas, Sherman, Michael Y.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2000
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11147965/
https://ncbi.nlm.nih.govhttps://doi.org/10.1379/1466-1268(2000)005<0139:hcpcfh>2.0.co;2
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