Group IVA Cytosolic Phospholipase A(2) Regulates the G(2)-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2

The G(2)-to-M transition (or prophase) checkpoint of the cell cycle is a critical regulator of mitotic entry. SIRT2, a tumor suppressor gene, contributes to the control of this checkpoint by blocking mitotic entry under cellular stress. However, the mechanism underlying both SIRT2 activation and reg...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Movahedi Naini, Said, Sheridan, Alice M., Force, Thomas, Shah, Jagesh V., Bonventre, Joseph V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589591/
https://ncbi.nlm.nih.gov/pubmed/26303530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00184-15
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