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Ceramide 1-Phosphate Is Required for the Translocation of Group IVA Cytosolic Phospholipase A(2) and Prostaglandin Synthesis

Little is known about the regulation of eicosanoid synthesis proximal to the activation of cytosolic phospholipase A(2)α (cPLA(2)α), the initial rate-limiting step. The current view is that cPLA(2)α associates with intracellular/phosphatidylcholine-rich membranes strictly via hydrophobic interaction...

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Détails bibliographiques
Auteurs principaux: Lamour, Nadia F., Subramanian, Preeti, Wijesinghe, Dayanjan S., Stahelin, Robert V., Bonventre, Joseph V., Chalfant, Charles E.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785377/
https://ncbi.nlm.nih.gov/pubmed/19632995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001677
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