IL-18: throwing off the shackles to boost anti-tumor immunity

par Dixon, Karen O., Kuchroo, Vijay K.
Publié dans Cell Res (2020)

Human disease mutations highlight the inhibitory function of TIM-3

par Dixon, Karen O., Das, Madhumita, Kuchroo, Vijay K.
Publié dans Nat Genet (2018)

Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members

par Dixon, Karen O., van der Kooij, Sandra W., Vignali, Dario A.A., van Kooten, Cees
Publié dans Eur J Immunol (2015)

Properdin and factor H production by human dendritic cells modulates their T‐cell stimulatory capacity and is regulated by IFN‐γ

par Dixon, Karen O., O'Flynn, Joseph, Klar‐Mohamad, Ngaisah, Daha, Mohamed R., van Kooten, Cees
Publié dans Eur J Immunol (2017)

Myeloperoxidase Directs Properdin-Mediated Complement Activation

par O'Flynn, Joseph, Dixon, Karen O., Faber Krol, Maria C., Daha, Mohamed R., van Kooten, Cees
Publié dans J Innate Immun (2014)

Functional anti-TIGIT antibodies regulate development of autoimmunity and anti-tumor immunity

par Dixon, Karen O., Schorer, Michelle, Nevin, James, Etminan, Yassaman, Amoozgar, Zohreh, Kondo, Takaaki, Kurtulus, Sema, Kassam, Nasim, Sobel, Raymond A., Fukumura, Dai, Jain, Rakesh K., Anderson, Ana C., Kuchroo, Vijay K., Joller, Nicole
Publié dans J Immunol (2018)

Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion

par Zhu, Chen, Dixon, Karen O., Newcomer, Kathleen, Gu, Guangxiang, Xiao, Sheng, Zaghouani, Sarah, Schramm, Markus A., Wang, Chao, Zhang, Huiyuan, Goto, Kouichiro, Christian, Elena, Rangachari, Manu, Rosenblatt-Rosen, Orit, Okada, Hitoshi, Mak, Tak, Singer, Meromit, Regev, Aviv, Kuchroo, Vijay
Publié dans Sci Adv (2021)

Endogenous glucocorticoid signaling regulates effector differentiation and development of dysfunction in CD8(+) T cells in the tumor microenvironment

par Acharya, Nandini, Madi, Asaf, Zhang, Huiyuan, Klapholz, Max, Escobar, Giulia, Dulberg, Shai, Christian, Elena, Ferreira, Michelle, Dixon, Karen O., Fell, Geoffrey, Tooley, Katherine, Mangani, Davide, Xia, Junrong, Singer, Meromit, Bosenberg, Marcus, Neuberg, Donna, Rozenblatt-Rosen, Orit, Regev, Aviv, Kuchroo, Vijay K., Anderson, Ana C.
Publié dans Immunity (2020)