Properdin and factor H production by human dendritic cells modulates their T‐cell stimulatory capacity and is regulated by IFN‐γ

Dendritic cells (DCs) and complement are both key members of the innate and adaptive immune response. Recent experimental mouse models have shown that production of alternative pathway (AP) components by DCs strongly affects their ability to activate and regulate T‐cell responses. In this study we i...

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Vydáno v:Eur J Immunol
Hlavní autoři: Dixon, Karen O., O'Flynn, Joseph, Klar‐Mohamad, Ngaisah, Daha, Mohamed R., van Kooten, Cees
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Innate immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363362/
https://ncbi.nlm.nih.gov/pubmed/28105653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646703
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