Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung(−/−)Msh2(−/−)...

Tekijä Kemmerich, Kristin, Dingler, Felix A., Rada, Cristina, Neuberger, Michael S.
Julkaistu 2012

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

Tekijä Dingler, Felix A., Kemmerich, Kristin, Neuberger, Michael S., Rada, Cristina
Julkaistu 2014

Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

Tekijä Baud, Matthias G.J., Bauer, Matthias R., Verduci, Lorena, Dingler, Felix A., Patel, Ketan J., Horil Roy, Deeptee, Joerger, Andreas C., Fersht, Alan R.
Julkaisussa Eur J Med Chem (2018)

A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C

Tekijä Bauer, Matthias R, Jones, Rhiannon N, Tareque, Raysa K, Springett, Bradley, Dingler, Felix A, Verduci, Lorena, Patel, Ketan J, Fersht, Alan R, Joerger, Andreas C, Spencer, John
Julkaisussa Future Med Chem (2019)

Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis

Tekijä Mahata, Bidesh, Zhang, Xiuwei, Kolodziejczyk, Aleksandra A., Proserpio, Valentina, Haim-Vilmovsky, Liora, Taylor, Angela E., Hebenstreit, Daniel, Dingler, Felix A., Moignard, Victoria, Göttgens, Berthold, Arlt, Wiebke, McKenzie, Andrew N.J., Teichmann, Sarah A.
Julkaistu 2014

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Tekijä Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.
Julkaisussa Nature (2017)

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Tekijä Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.
Julkaisussa Nature (2017)

Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1

Tekijä Alsøe, Lene, Sarno, Antonio, Carracedo, Sergio, Domanska, Diana, Dingler, Felix, Lirussi, Lisa, SenGupta, Tanima, Tekin, Nuriye Basdag, Jobert, Laure, Alexandrov, Ludmil B., Galashevskaya, Anastasia, Rada, Cristina, Sandve, Geir Kjetil, Rognes, Torbjørn, Krokan, Hans E., Nilsen, Hilde
Julkaisussa Sci Rep (2017)

The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID

Tekijä Safavi, Shiva, Larouche, Ariane, Zahn, Astrid, Patenaude, Anne-Marie, Domanska, Diana, Dionne, Kiersten, Rognes, Torbjørn, Dingler, Felix, Kang, Seong-Kwi, Liu, Yan, Johnson, Nathalie, Hébert, Josée, Verdun, Ramiro E, Rada, Cristina A, Vega, Francisco, Nilsen, Hilde, Di Noia, Javier M
Julkaisussa NAR Cancer (2020)

The uracil–DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID

Tekijä Safavi, Shiva, Larouche, Ariane, Zahn, Astrid, Patenaude, Anne-Marie, Domanska, Diana, Dionne, Kiersten, Rognes, Torbjørn, Dingler, Felix, Kang, Seong-Kwi, Liu, Yan, Johnson, Nathalie, Hébert, Josée, Verdun, Ramiro E, Rada, Cristina A, Vega, Francisco, Nilsen, Hilde, Noia, Javier M D
Julkaisussa NAR Cancer (2021)

Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

Tekijä Wang, Meng, Brandt, Laura T.L., Wang, Xiaonan, Russell, Holly, Mitchell, Emily, Kamimae-Lanning, Ashley N., Brown, Jill M., Dingler, Felix A., Garaycoechea, Juan I., Isobe, Tomoya, Kinston, Sarah J., Gu, Muxin, Vassiliou, George S., Wilson, Nicola K., Göttgens, Berthold, Patel, Ketan J.
Julkaisussa Mol Cell (2023)

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

Tekijä Dingler, Felix A., Wang, Meng, Mu, Anfeng, Millington, Christopher L., Oberbeck, Nina, Watcham, Sam, Pontel, Lucas B., Kamimae-Lanning, Ashley N., Langevin, Frederic, Nadler, Camille, Cordell, Rebecca L., Monks, Paul S., Yu, Rui, Wilson, Nicola K., Hira, Asuka, Yoshida, Kenichi, Mori, Minako, Okamoto, Yusuke, Okuno, Yusuke, Muramatsu, Hideki, Shiraishi, Yuichi, Kobayashi, Masayuki, Moriguchi, Toshinori, Osumi, Tomoo, Kato, Motohiro, Miyano, Satoru, Ito, Etsuro, Kojima, Seiji, Yabe, Hiromasa, Yabe, Miharu, Matsuo, Keitaro, Ogawa, Seishi, Göttgens, Berthold, Hodskinson, Michael R.G., Takata, Minoru, Patel, Ketan J.
Julkaisussa Mol Cell (2020)