Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs

von Bauer, Matthias R., Jones, Rhiannon N., Baud, Matthias G. J., Wilcken, Rainer, Boeckler, Frank M., Fersht, Alan R., Joerger, Andreas C., Spencer, John
Veröffentlicht in ACS Chem Biol (2016)

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm

von Bauer, Matthias R., Krämer, Andreas, Settanni, Giovanni, Jones, Rhiannon N., Ni, Xiaomin, Khan Tareque, Raysa, Fersht, Alan R., Spencer, John, Joerger, Andreas C.
Veröffentlicht in ACS Chem Biol (2020)

A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C

von Bauer, Matthias R, Jones, Rhiannon N, Tareque, Raysa K, Springett, Bradley, Dingler, Felix A, Verduci, Lorena, Patel, Ketan J, Fersht, Alan R, Joerger, Andreas C, Spencer, John
Veröffentlicht in Future Med Chem (2019)

A synthetic, catalytic and theoretical investigation of an unsymmetrical SCN pincer palladacycle

von Roffe, Gavin W., Boonseng, Sarote, Baltus, Christine B., Coles, Simon J., Day, Iain J., Jones, Rhiannon N., Press, Neil J., Ruiz, Mario, Tizzard, Graham J., Cox, Hazel, Spencer, John
Veröffentlicht in R Soc Open Sci (2016)