A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells

par Brewer, Thomas F., Burgos-Barragan, Guillermo, Wit, Niek, Patel, Ketan J., Chang, Christopher J.
Publié dans Chem Sci (2017)

Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells

par Bruemmer, Kevin J., Walvoord, Ryan R., Brewer, Thomas F., Burgos-Barragan, Guillermo, Wit, Niek, Pontel, Lucas B., Patel, Ketan J., Chang, Christopher J.
Publié dans J Am Chem Soc (2017)

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

par Pontel, Lucas B., Rosado, Ivan V., Burgos-Barragan, Guillermo, Garaycoechea, Juan I., Yu, Rui, Arends, Mark J., Chandrasekaran, Gayathri, Broecker, Verena, Wei, Wei, Liu, Limin, Swenberg, James A., Crossan, Gerry P., Patel, Ketan J.
Publié dans Mol Cell (2015)

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

par Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.
Publié dans Nature (2017)

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

par Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.
Publié dans Nature (2017)

Increased formate overflow is a hallmark of oxidative cancer

par Meiser, Johannes, Schuster, Anne, Pietzke, Matthias, Vande Voorde, Johan, Athineos, Dimitris, Oizel, Kristell, Burgos-Barragan, Guillermo, Wit, Niek, Dhayade, Sandeep, Morton, Jennifer P., Dornier, Emmanuel, Sumpton, David, Mackay, Gillian M., Blyth, Karen, Patel, Ketan J., Niclou, Simone P., Vazquez, Alexei
Publié dans Nat Commun (2018)