Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung(−/−)Msh2(−/−)...

gan Kemmerich, Kristin, Dingler, Felix A., Rada, Cristina, Neuberger, Michael S.
Cyhoeddwyd 2012

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

gan Dingler, Felix A., Kemmerich, Kristin, Neuberger, Michael S., Rada, Cristina
Cyhoeddwyd 2014

Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

gan Baud, Matthias G.J., Bauer, Matthias R., Verduci, Lorena, Dingler, Felix A., Patel, Ketan J., Horil Roy, Deeptee, Joerger, Andreas C., Fersht, Alan R.
Cyhoeddwyd yn Eur J Med Chem (2018)

A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C

gan Bauer, Matthias R, Jones, Rhiannon N, Tareque, Raysa K, Springett, Bradley, Dingler, Felix A, Verduci, Lorena, Patel, Ketan J, Fersht, Alan R, Joerger, Andreas C, Spencer, John
Cyhoeddwyd yn Future Med Chem (2019)

Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis

gan Mahata, Bidesh, Zhang, Xiuwei, Kolodziejczyk, Aleksandra A., Proserpio, Valentina, Haim-Vilmovsky, Liora, Taylor, Angela E., Hebenstreit, Daniel, Dingler, Felix A., Moignard, Victoria, Göttgens, Berthold, Arlt, Wiebke, McKenzie, Andrew N.J., Teichmann, Sarah A.
Cyhoeddwyd 2014

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

gan Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.
Cyhoeddwyd yn Nature (2017)

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

gan Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.
Cyhoeddwyd yn Nature (2017)

Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1

gan Alsøe, Lene, Sarno, Antonio, Carracedo, Sergio, Domanska, Diana, Dingler, Felix, Lirussi, Lisa, SenGupta, Tanima, Tekin, Nuriye Basdag, Jobert, Laure, Alexandrov, Ludmil B., Galashevskaya, Anastasia, Rada, Cristina, Sandve, Geir Kjetil, Rognes, Torbjørn, Krokan, Hans E., Nilsen, Hilde
Cyhoeddwyd yn Sci Rep (2017)

The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID

gan Safavi, Shiva, Larouche, Ariane, Zahn, Astrid, Patenaude, Anne-Marie, Domanska, Diana, Dionne, Kiersten, Rognes, Torbjørn, Dingler, Felix, Kang, Seong-Kwi, Liu, Yan, Johnson, Nathalie, Hébert, Josée, Verdun, Ramiro E, Rada, Cristina A, Vega, Francisco, Nilsen, Hilde, Di Noia, Javier M
Cyhoeddwyd yn NAR Cancer (2020)

Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

gan Wang, Meng, Brandt, Laura T.L., Wang, Xiaonan, Russell, Holly, Mitchell, Emily, Kamimae-Lanning, Ashley N., Brown, Jill M., Dingler, Felix A., Garaycoechea, Juan I., Isobe, Tomoya, Kinston, Sarah J., Gu, Muxin, Vassiliou, George S., Wilson, Nicola K., Göttgens, Berthold, Patel, Ketan J.
Cyhoeddwyd yn Mol Cell (2023)

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

gan Dingler, Felix A., Wang, Meng, Mu, Anfeng, Millington, Christopher L., Oberbeck, Nina, Watcham, Sam, Pontel, Lucas B., Kamimae-Lanning, Ashley N., Langevin, Frederic, Nadler, Camille, Cordell, Rebecca L., Monks, Paul S., Yu, Rui, Wilson, Nicola K., Hira, Asuka, Yoshida, Kenichi, Mori, Minako, Okamoto, Yusuke, Okuno, Yusuke, Muramatsu, Hideki, Shiraishi, Yuichi, Kobayashi, Masayuki, Moriguchi, Toshinori, Osumi, Tomoo, Kato, Motohiro, Miyano, Satoru, Ito, Etsuro, Kojima, Seiji, Yabe, Hiromasa, Yabe, Miharu, Matsuo, Keitaro, Ogawa, Seishi, Göttgens, Berthold, Hodskinson, Michael R.G., Takata, Minoru, Patel, Ketan J.
Cyhoeddwyd yn Mol Cell (2020)