Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells

av Deng, Xiaobing, Friedman, Eileen
Publicerad 2014

Mirk/Dyrk1B Maintains the Viability of Quiescent Pancreatic Cancer Cells by Reducing Levels of Reactive Oxygen Species

av Deng, Xiaobing, Ewton, Daina Z., Friedman, Eileen
Publicerad 2009

Mirk/dyrk1B kinase is upregulated following inhibition of mTOR

av Deng, Xiaobing, Hu, Jing, Ewton, Daina Z., Friedman, Eileen
Publicerad 2014

Mirk kinase inhibition targets ovarian cancer ascites

av Deng, Xiaobing, Hu, Jing, Cunningham, Mary J., Friedman, Eileen
Publicerad 2014

The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species

av Deng, Xiaobing, Mercer, Stephen E., Sun, Chi-Yu, Friedman, Eileen
Publicerad 2014

A novel allosteric inhibitor that prevents IKKβ activation

av Liu, Hongbo, Liang, Hao, Meng, Hu, Deng, Xiaobing, Zhang, Xiaoling, Lai, Luhua
I publikationen Medchemcomm (2018)

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

av Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
I publikationen Front Chem (2018)

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

av Li, Cong, Deng, Xiaobing, Xie, Xiaowen, Liu, Ying, Friedmann Angeli, José Pedro, Lai, Luhua
I publikationen Front Pharmacol (2018)

MIRK/DYRK1B MEDIATES SURVIVAL DURING THE DIFFERENTIATION OF C2C12 MYOBLASTS

av Mercer, Stephen E., Ewton, Daina Z., Deng, Xiaobing, Lim, Seunghwan, Mazur, Thomas R., Friedman, Eileen
Publicerad 2005

Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

av Han, Fangbin, Lin, Songwen, Liu, Peng, Liu, Xiujie, Tao, Jing, Deng, Xiaobing, Yi, Chongqin, Xu, Heng
I publikationen ACS Med Chem Lett (2015)

Rational design of selective allosteric inhibitors of PHDGH and serine synthesis with in vivo activity

av Wang, Qian, Liberti, Maria V., Liu, Pei, Deng, Xiaobing, Liu, Ying, Locasale, Jason W., Lai, Luhua
I publikationen Cell Chem Biol (2016)

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

av Liu, Pei, Liu, Hongbo, Sun, Qi, Liang, Hao, Li, Chunmei, Deng, Xiaobing, Liu, Ying, Lai, Luhua
I publikationen Eur J Med Chem (2020)

The Ets protein Pointed prevents both premature differentiation and dedifferentiation of Drosophila intermediate neural progenitors

av Xie, Yonggang, Li, Xiaosu, Deng, Xiaobing, Hou, Yanjun, O'Hara, Krysten, Urso, Andreacarola, Peng, Ying, Chen, Li, Zhu, Sijun
I publikationen Development (2016)

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

av Ewton, Daina Z., Hu, Jing, Vilenchik, Maria, Deng, Xiaobing, Luk, Kin-chun, Polonskaia, Ann, Hoffman, Ann F., Zipf, Karen, Boylan, John F., Friedman, Eileen A.
Publicerad 2011