Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells

door Deng, Xiaobing, Friedman, Eileen
Gepubliceerd in 2014

Mirk/Dyrk1B Maintains the Viability of Quiescent Pancreatic Cancer Cells by Reducing Levels of Reactive Oxygen Species

door Deng, Xiaobing, Ewton, Daina Z., Friedman, Eileen
Gepubliceerd in 2009

Mirk/dyrk1B kinase is upregulated following inhibition of mTOR

door Deng, Xiaobing, Hu, Jing, Ewton, Daina Z., Friedman, Eileen
Gepubliceerd in 2014

Mirk kinase inhibition targets ovarian cancer ascites

door Deng, Xiaobing, Hu, Jing, Cunningham, Mary J., Friedman, Eileen
Gepubliceerd in 2014

The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species

door Deng, Xiaobing, Mercer, Stephen E., Sun, Chi-Yu, Friedman, Eileen
Gepubliceerd in 2014

A novel allosteric inhibitor that prevents IKKβ activation

door Liu, Hongbo, Liang, Hao, Meng, Hu, Deng, Xiaobing, Zhang, Xiaoling, Lai, Luhua
Gepubliceerd in Medchemcomm (2018)

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

door Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
Gepubliceerd in Front Chem (2018)

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

door Li, Cong, Deng, Xiaobing, Xie, Xiaowen, Liu, Ying, Friedmann Angeli, José Pedro, Lai, Luhua
Gepubliceerd in Front Pharmacol (2018)

MIRK/DYRK1B MEDIATES SURVIVAL DURING THE DIFFERENTIATION OF C2C12 MYOBLASTS

door Mercer, Stephen E., Ewton, Daina Z., Deng, Xiaobing, Lim, Seunghwan, Mazur, Thomas R., Friedman, Eileen
Gepubliceerd in 2005

Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

door Han, Fangbin, Lin, Songwen, Liu, Peng, Liu, Xiujie, Tao, Jing, Deng, Xiaobing, Yi, Chongqin, Xu, Heng
Gepubliceerd in ACS Med Chem Lett (2015)

Rational design of selective allosteric inhibitors of PHDGH and serine synthesis with in vivo activity

door Wang, Qian, Liberti, Maria V., Liu, Pei, Deng, Xiaobing, Liu, Ying, Locasale, Jason W., Lai, Luhua
Gepubliceerd in Cell Chem Biol (2016)

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

door Liu, Pei, Liu, Hongbo, Sun, Qi, Liang, Hao, Li, Chunmei, Deng, Xiaobing, Liu, Ying, Lai, Luhua
Gepubliceerd in Eur J Med Chem (2020)

The Ets protein Pointed prevents both premature differentiation and dedifferentiation of Drosophila intermediate neural progenitors

door Xie, Yonggang, Li, Xiaosu, Deng, Xiaobing, Hou, Yanjun, O'Hara, Krysten, Urso, Andreacarola, Peng, Ying, Chen, Li, Zhu, Sijun
Gepubliceerd in Development (2016)

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

door Ewton, Daina Z., Hu, Jing, Vilenchik, Maria, Deng, Xiaobing, Luk, Kin-chun, Polonskaia, Ann, Hoffman, Ann F., Zipf, Karen, Boylan, John F., Friedman, Eileen A.
Gepubliceerd in 2011