Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells

nork Deng, Xiaobing, Friedman, Eileen
Argitaratua 2014

Mirk/Dyrk1B Maintains the Viability of Quiescent Pancreatic Cancer Cells by Reducing Levels of Reactive Oxygen Species

nork Deng, Xiaobing, Ewton, Daina Z., Friedman, Eileen
Argitaratua 2009

Mirk/dyrk1B kinase is upregulated following inhibition of mTOR

nork Deng, Xiaobing, Hu, Jing, Ewton, Daina Z., Friedman, Eileen
Argitaratua 2014

Mirk kinase inhibition targets ovarian cancer ascites

nork Deng, Xiaobing, Hu, Jing, Cunningham, Mary J., Friedman, Eileen
Argitaratua 2014

The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species

nork Deng, Xiaobing, Mercer, Stephen E., Sun, Chi-Yu, Friedman, Eileen
Argitaratua 2014

A novel allosteric inhibitor that prevents IKKβ activation

nork Liu, Hongbo, Liang, Hao, Meng, Hu, Deng, Xiaobing, Zhang, Xiaoling, Lai, Luhua
Argitaratua izan da Medchemcomm (2018)

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

nork Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
Argitaratua izan da Front Chem (2018)

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

nork Li, Cong, Deng, Xiaobing, Xie, Xiaowen, Liu, Ying, Friedmann Angeli, José Pedro, Lai, Luhua
Argitaratua izan da Front Pharmacol (2018)

MIRK/DYRK1B MEDIATES SURVIVAL DURING THE DIFFERENTIATION OF C2C12 MYOBLASTS

nork Mercer, Stephen E., Ewton, Daina Z., Deng, Xiaobing, Lim, Seunghwan, Mazur, Thomas R., Friedman, Eileen
Argitaratua 2005

Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

nork Han, Fangbin, Lin, Songwen, Liu, Peng, Liu, Xiujie, Tao, Jing, Deng, Xiaobing, Yi, Chongqin, Xu, Heng
Argitaratua izan da ACS Med Chem Lett (2015)

Rational design of selective allosteric inhibitors of PHDGH and serine synthesis with in vivo activity

nork Wang, Qian, Liberti, Maria V., Liu, Pei, Deng, Xiaobing, Liu, Ying, Locasale, Jason W., Lai, Luhua
Argitaratua izan da Cell Chem Biol (2016)

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

nork Liu, Pei, Liu, Hongbo, Sun, Qi, Liang, Hao, Li, Chunmei, Deng, Xiaobing, Liu, Ying, Lai, Luhua
Argitaratua izan da Eur J Med Chem (2020)

The Ets protein Pointed prevents both premature differentiation and dedifferentiation of Drosophila intermediate neural progenitors

nork Xie, Yonggang, Li, Xiaosu, Deng, Xiaobing, Hou, Yanjun, O'Hara, Krysten, Urso, Andreacarola, Peng, Ying, Chen, Li, Zhu, Sijun
Argitaratua izan da Development (2016)

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

nork Ewton, Daina Z., Hu, Jing, Vilenchik, Maria, Deng, Xiaobing, Luk, Kin-chun, Polonskaia, Ann, Hoffman, Ann F., Zipf, Karen, Boylan, John F., Friedman, Eileen A.
Argitaratua 2011