Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells

per Deng, Xiaobing, Friedman, Eileen
Publicat 2014

Mirk/Dyrk1B Maintains the Viability of Quiescent Pancreatic Cancer Cells by Reducing Levels of Reactive Oxygen Species

per Deng, Xiaobing, Ewton, Daina Z., Friedman, Eileen
Publicat 2009

Mirk/dyrk1B kinase is upregulated following inhibition of mTOR

per Deng, Xiaobing, Hu, Jing, Ewton, Daina Z., Friedman, Eileen
Publicat 2014

Mirk kinase inhibition targets ovarian cancer ascites

per Deng, Xiaobing, Hu, Jing, Cunningham, Mary J., Friedman, Eileen
Publicat 2014

The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species

per Deng, Xiaobing, Mercer, Stephen E., Sun, Chi-Yu, Friedman, Eileen
Publicat 2014

A novel allosteric inhibitor that prevents IKKβ activation

per Liu, Hongbo, Liang, Hao, Meng, Hu, Deng, Xiaobing, Zhang, Xiaoling, Lai, Luhua
Publicat a Medchemcomm (2018)

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

per Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
Publicat a Front Chem (2018)

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

per Li, Cong, Deng, Xiaobing, Xie, Xiaowen, Liu, Ying, Friedmann Angeli, José Pedro, Lai, Luhua
Publicat a Front Pharmacol (2018)

MIRK/DYRK1B MEDIATES SURVIVAL DURING THE DIFFERENTIATION OF C2C12 MYOBLASTS

per Mercer, Stephen E., Ewton, Daina Z., Deng, Xiaobing, Lim, Seunghwan, Mazur, Thomas R., Friedman, Eileen
Publicat 2005

Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

per Han, Fangbin, Lin, Songwen, Liu, Peng, Liu, Xiujie, Tao, Jing, Deng, Xiaobing, Yi, Chongqin, Xu, Heng
Publicat a ACS Med Chem Lett (2015)

Rational design of selective allosteric inhibitors of PHDGH and serine synthesis with in vivo activity

per Wang, Qian, Liberti, Maria V., Liu, Pei, Deng, Xiaobing, Liu, Ying, Locasale, Jason W., Lai, Luhua
Publicat a Cell Chem Biol (2016)

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

per Liu, Pei, Liu, Hongbo, Sun, Qi, Liang, Hao, Li, Chunmei, Deng, Xiaobing, Liu, Ying, Lai, Luhua
Publicat a Eur J Med Chem (2020)

The Ets protein Pointed prevents both premature differentiation and dedifferentiation of Drosophila intermediate neural progenitors

per Xie, Yonggang, Li, Xiaosu, Deng, Xiaobing, Hou, Yanjun, O'Hara, Krysten, Urso, Andreacarola, Peng, Ying, Chen, Li, Zhu, Sijun
Publicat a Development (2016)

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

per Ewton, Daina Z., Hu, Jing, Vilenchik, Maria, Deng, Xiaobing, Luk, Kin-chun, Polonskaia, Ann, Hoffman, Ann F., Zipf, Karen, Boylan, John F., Friedman, Eileen A.
Publicat 2011