Rodent models in Down syndrome research: impact and future opportunities

Por Herault, Yann, Delabar, Jean M., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Yu, Eugene, Brault, Veronique
Publicado no Dis Model Mech (2017)

Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A

Por Guedj, Fayçal, Sébrié, Catherine, Rivals, Isabelle, Ledru, Aurelie, Paly, Evelyne, Bizot, Jean C., Smith, Desmond, Rubin, Edward, Gillet, Brigitte, Arbones, Mariona, Delabar, Jean M.
Publicado em 2009

DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome

Por Najas, Sònia, Arranz, Juan, Lochhead, Pamela A., Ashford, Anne L., Oxley, David, Delabar, Jean M., Cook, Simon J., Barallobre, María José, Arbonés, Maria L.
Publicado no EBioMedicine (2015)

Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models

Por Souchet, Benoit, Guedj, Fayçal, Penke-Verdier, Zsuza, Daubigney, Fabrice, Duchon, Arnaud, Herault, Yann, Bizot, Jean-Charles, Janel, Nathalie, Créau, Nicole, Delatour, Benoit, Delabar, Jean M.
Publicado no Front Behav Neurosci (2015)

Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase

Por Régnier, Vinciane, Billard, Jean-Marie, Gupta, Sapna, Potier, Brigitte, Woerner, Stéphanie, Paly, Evelyne, Ledru, Aurélie, David, Sabrina, Luilier, Sabrina, Bizot, Jean-Charles, Vacano, Guido, Kraus, Jan P., Patterson, David, Kruger, Warren D., Delabar, Jean M., London, Jaqueline
Publicado em 2012

Trisomy for Synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes

Por Cossec, Jack-Christophe, Lavaur, Jérémie, Berman, Diego E., Rivals, Isabelle, Hoischen, Alexander, Stora, Samantha, Ripoll, Clémentine, Mircher, Clotilde, Grattau, Yann, OlivoMarin, Jean-Christophe, de Chaumont, Fabrice, Lecourtois, Magalie, Antonarakis, Stylianos E., Veltman, Joris A., Delabar, Jean M., Duyckaerts, Charles, Di Paolo, Gilbert, Potier, Marie-Claude
Publicado em 2012

Genotype–phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

Por Lyle, Robert, Béna, Frédérique, Gagos, Sarantis, Gehrig, Corinne, Lopez, Gipsy, Schinzel, Albert, Lespinasse, James, Bottani, Armand, Dahoun, Sophie, Taine, Laurence, Doco-Fenzy, Martine, Cornillet-Lefèbvre, Pascale, Pelet, Anna, Lyonnet, Stanislas, Toutain, Annick, Colleaux, Laurence, Horst, Jürgen, Kennerknecht, Ingo, Wakamatsu, Nobuaki, Descartes, Maria, Franklin, Judy C, Florentin-Arar, Lina, Kitsiou, Sophia, Aït Yahya-Graison, Emilie, Costantine, Maher, Sinet, Pierre-Marie, Delabar, Jean M, Antonarakis, Stylianos E
Publicado em 2009

The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome

Por Sailani, M. Reza, Makrythanasis, Periklis, Valsesia, Armand, Santoni, Federico A., Deutsch, Samuel, Popadin, Konstantin, Borel, Christelle, Migliavacca, Eugenia, Sharp, Andrew J., Duriaux Sail, Genevieve, Falconnet, Emilie, Rabionet, Kelly, Serra-Juhé, Clara, Vicari, Stefano, Laux, Daniela, Grattau, Yann, Dembour, Guy, Megarbane, Andre, Touraine, Renaud, Stora, Samantha, Kitsiou, Sofia, Fryssira, Helena, Chatzisevastou-Loukidou, Chariklia, Kanavakis, Emmanouel, Merla, Giuseppe, Bonnet, Damien, Pérez-Jurado, Luis A., Estivill, Xavier, Delabar, Jean M., Antonarakis, Stylianos E.
Publicado em 2013