Preclinical pharmacokinetics, pharmacodynamics, and activity of a humanized anti-CD40 antibody (SGN-40) in rodents and non-human primates

gan Kelley, Sean K, Gelzleichter, Thomas, Xie, Dong, Lee, Wyne P, Darbonne, Walter C, Qureshi, Ferhan, Kissler, Kim, Oflazoglu, Ezogelin, Grewal, Iqbal S
Cyhoeddwyd 2006

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

gan Tian, Hua, Callahan, Christopher A., DuPree, Kelly J., Darbonne, Walter C., Ahn, Christina P., Scales, Suzie J., de Sauvage, Frederic J.
Cyhoeddwyd 2009

Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells

gan Chen, Weiwei, Tang, Tracy, Eastham-Anderson, Jeff, Dunlap, Debra, Alicke, Bruno, Nannini, Michelle, Gould, Stephen, Yauch, Robert, Modrusan, Zora, DuPree, Kelly J., Darbonne, Walter C., Plowman, Greg, de Sauvage, Frederic J., Callahan, Christopher A.
Cyhoeddwyd 2011

Antitherapeutic antibody-mediated hepatotoxicity of recombinant human Apo2L/TRAIL in the cynomolgus monkey

gan Zuch de Zafra, Christina L, Ashkenazi, Avi, Darbonne, Walter C, Cheu, Melissa, Totpal, Klara, Ortega, Shirley, Flores, Heather, Walker, Mark D, Kabakoff, Bruce, Lum, Bert L, Mounho-Zamora, Barbara J, Marsters, Scot A, Dybdal, Noël O
Cyhoeddwyd yn Cell Death Dis (2016)

Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors

gan LoRusso, Patricia M., Rudin, Charles M., Reddy, Josina C., Tibes, Raoul, Weiss, Glen J., Borad, Mitesh J., Hann, Christine L., Brahmer, Julie R., Chang, Ilsung, Darbonne, Walter C., Graham, Richard A., Zerivitz, Kenn L., Low, Jennifer A., Von Hoff, Daniel D.
Cyhoeddwyd yn Clin Cancer Res (2011)