Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

por Barbour, Haithem, Daou, Salima, Hendzel, Michael, Affar, El Bachir
Publicado en Nat Commun (2020)

Electron transfer dissociation (ETD): The mass spectrometric breakthrough essential for O-GlcNAc protein site assignments – A study of the O-GlcNAcylated protein Host Cell Factor C...

por Myers, Samuel A., Daou, Salima, Affar, El Bachir, Burlingame, AL
Publicado 2013

The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis

por Bottardi, Stefania, Mavoungou, Lionel, Pak, Helen, Daou, Salima, Bourgoin, Vincent, Lakehal, Yahia A., Affar, El Bachir, Milot, Eric
Publicado en PLoS Genet (2014)

Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway

por Daou, Salima, Mashtalir, Nazar, Hammond-Martel, Ian, Pak, Helen, Yu, Helen, Sui, Guangchao, Vogel, Jodi L., Kristie, Thomas M., Affar, El Bachir
Publicado 2011

Undetectable histone O-GlcNAcylation in mammalian cells

por Gagnon, Jessica, Daou, Salima, Zamorano, Natalia, Iannantuono, Nicholas VG, Hammond-Martel, Ian, Mashtalir, Nazar, Bonneil, Eric, Wurtele, Hugo, Thibault, Pierre, Affar, El Bachir
Publicado en Epigenetics (2015)

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

por Yu, Helen, Mashtalir, Nazar, Daou, Salima, Hammond-Martel, Ian, Ross, Julie, Sui, Guangchao, Hart, Gerald W., Rauscher, Frank J., Drobetsky, Elliot, Milot, Eric, Shi, Yang, Affar, El Bachir
Publicado 2010

Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

por Yu, Helen, Pak, Helen, Hammond-Martel, Ian, Ghram, Mehdi, Rodrigue, Amélie, Daou, Salima, Barbour, Haithem, Corbeil, Luc, Hébert, Josée, Drobetsky, Elliot, Masson, Jean Yves, Di Noia, Javier M., Affar, El Bachir
Publicado 2014

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer

por Daou, Salima, Hammond-Martel, Ian, Mashtalir, Nazar, Barbour, Haithem, Gagnon, Jessica, Iannantuono, Nicholas V. G., Nkwe, Nadine Sen, Motorina, Alena, Pak, Helen, Yu, Helen, Wurtele, Hugo, Milot, Eric, Mallette, Frédérick A., Carbone, Michele, Affar, El Bachir
Publicado en J Biol Chem (2015)

A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency

por Daou, Salima, Talukdar, Manisha, Tang, Jinle, Dong, Beihua, Banerjee, Shuvojit, Li, Yize, Duffy, Nicole M., Ogunjimi, Abiodun A., Gaughan, Christina, Jha, Babal K., Gish, Gerald, Tavernier, Nicolas, Mao, Daniel, Weiss, Susan R., Huang, Hao, Silverman, Robert H., Sicheri, Frank
Publicado en Proc Natl Acad Sci U S A (2020)

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1

por Daou, Salima, Barbour, Haithem, Ahmed, Oumaima, Masclef, Louis, Baril, Caroline, Sen Nkwe, Nadine, Tchelougou, Daméhan, Uriarte, Maxime, Bonneil, Eric, Ceccarelli, Derek, Mashtalir, Nazar, Tanji, Mika, Masson, Jean-Yves, Thibault, Pierre, Sicheri, Frank, Yang, Haining, Carbone, Michele, Therrien, Marc, Affar, El Bachir
Publicado en Nat Commun (2018)

Functional characterization of a PROTAC directed against BRAF mutant V600E

por Posternak, Ganna, Tang, Xiaojing, Maisonneuve, Pierre, Jin, Ting, Lavoie, Hugo, Daou, Salima, Orlicky, Stephen, de Rugy, Theo Goullet, Caldwell, Lauren, Chan, Kin, Aman, Ahmed, Prakesch, Michael, Poda, Gennady, Mader, Pavel, Wong, Cassandra, Maier, Stefan, Kitaygorodsky, Julia, Larsen, Brett, Colwill, Karen, Yin, Zhe, Ceccarelli, Derek F., Batey, Robert A., Taipale, Mikko, Kurinov, Igor, Uehling, David, Wrana, Jeff, Durocher, Daniel, Gingras, Anne-Claude, Al-Awar, Rima, Therrien, Marc, Sicheri, Frank
Publicado en Nat Chem Biol (2020)