Comparison of three rapamycin dosing schedules in A/J Tsc2(+/- )mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous...

Por Woodrum, Chelsey, Nobil, Alison, Dabora, Sandra L
Publicado em 2010

Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model

Por Rauktys, Aubrey, Lee, Nancy, Lee, Laifong, Dabora, Sandra L
Publicado em 2008

Tuberous sclerosis preclinical studies: timing of treatment, combination of a rapamycin analog (CCI-779) and interferon-gamma, and comparison of rapamycin to CCI-779

Por Messina, Michael P, Rauktys, Aubrey, Lee, Laifong, Dabora, Sandra L
Publicado em 2007

Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models

Por Lee, Nancy, Woodrum, Chelsey L, Nobil, Alison M, Rauktys, Aubrey E, Messina, Michael P, Dabora, Sandra L
Publicado em 2009

PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR

Por Zhang, Hongbing, Bajraszewski, Natalia, Wu, Erxi, Wang, Hongwei, Moseman, Annie P., Dabora, Sandra L., Griffin, James D., Kwiatkowski, David J.
Publicado em 2007

Association between a High-Expressing Interferon-γ Allele and a Lower Frequency of Kidney Angiomyolipomas in TSC2 Patients

Por Dabora, Sandra L., Roberts, Penelope, Nieto, Andres, Perez, Ron, Jozwiak, Sergiusz, Franz, David, Bissler, John, Thiele, Elizabeth A., Sims, Katherine, Kwiatkowski, David J.
Publicado em 2002

Tsc2-Rheb Signaling Regulates EphA-Mediated Axon Guidance

Por Nie, Du-yu, Di Nardo, Alessia, Han, Juliette M., Baharanyi, Hasani, Kramvis, Ioannis, Huynh, ThanhThao, Dabora, Sandra, Codeluppi, Simone, Pandolfi, Pier Paolo, Pasquale, Elena B., Sahin, Mustafa
Publicado em 2010

Similar Trends in Serum VEGF-D Levels and Kidney Angiomyolipoma Responses with Longer Duration Sirolimus Treatment in Adults with Tuberous Sclerosis

Por Malinowska, Izabela A., Lee, Nancy, Kumar, Vidhya, Thiele, Elizabeth A., Franz, David Neal, Ashwal, Stephen, Sagalowsky, Arthur, DiMario, Francis J., Cutler, Drew, Krueger, Darcy, Camposano, Susana, Paolini, Jan, Dabora, Sandra L.
Publicado em 2013

Mutational Analysis in a Cohort of 224 Tuberous Sclerosis Patients Indicates Increased Severity of TSC2, Compared with TSC1, Disease in Multiple Organs

Por Dabora, Sandra L., Jozwiak, Sergiusz, Franz, David Neal, Roberts, Penelope S., Nieto, Andres, Chung, Joon, Choy, Yew-Sing, Reeve, Mary Pat, Thiele, Elizabeth, Egelhoff, John C., Kasprzyk-Obara, Jolanta, Domanska-Pakiela, Dorota, Kwiatkowski, David J.
Publicado em 2001

Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease

Por Dabora, Sandra L., Franz, David Neal, Ashwal, Stephen, Sagalowsky, Arthur, DiMario, Francis J., Miles, Daniel, Cutler, Drew, Krueger, Darcy, Uppot, Raul N., Rabenou, Rahmin, Camposano, Susana, Paolini, Jan, Fennessy, Fiona, Lee, Nancy, Woodrum, Chelsey, Manola, Judith, Garber, Judy, Thiele, Elizabeth A.
Publicado em 2011