Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models

BACKGROUND: Tuberous sclerosis complex (TSC) is an autosomal dominant tumor suppressor syndrome, characterized by hamartomatous growths in the brain, skin, kidneys, lungs, and heart, which lead to significant morbidity. TSC is caused by mutations in the TSC1 or TSC2 genes, whose products, hamartin a...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Lee, Nancy, Woodrum, Chelsey L, Nobil, Alison M, Rauktys, Aubrey E, Messina, Michael P, Dabora, Sandra L
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670829/
https://ncbi.nlm.nih.gov/pubmed/19368729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-8
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla