Comparison of three rapamycin dosing schedules in A/J Tsc2(+/- )mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors

BACKGROUND: Tuberous Sclerosis Complex (TSC) is an autosomal dominant tumor disorder characterized by the growth of hamartomas in various organs including the kidney, brain, skin, lungs, and heart. Rapamycin has been shown to reduce the size of kidney angiomyolipomas associated with TSC; however, tu...

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Detaylı Bibliyografya
Asıl Yazarlar: Woodrum, Chelsey, Nobil, Alison, Dabora, Sandra L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834646/
https://ncbi.nlm.nih.gov/pubmed/20146790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-14
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