Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin

par Trzoss, Lynnie, Fukuda, Takashi, Costa-Lotufo, Letícia V., Jimenez, Paula, La Clair, James J., Fenical, William
Publié 2014

Advance of Seriniquinone Analogues as Melanoma Agents

par Hammons, Justin C., Trzoss, Lynnie, Jimenez, Paula C., Hirata, Amanda S., Costa-Lotufo, Leticia V., La Clair, James J., Fenical, William
Publié dans ACS Med Chem Lett (2019)

Galenia africana plant extract exhibits cytotoxicity in breast cancer cells by inducing multiple programmed cell death pathways

par Mohamed, Luqmaan, Chakraborty, Suparna, ArulJothi, K.N., Mabasa, Lawrence, Sayah, Kenza, Costa-Lotufo, Leticia V., Jardine, Anwar, Prince, Sharon
Publié dans Saudi Pharm J (2020)

Enriching cancer pharmacology with drugs of marine origin

par Jimenez, Paula C., Wilke, Diego V., Branco, Paola C., Bauermeister, Anelize, Rezende‐Teixeira, Paula, Gaudêncio, Susana P., Costa‐Lotufo, Leticia V.
Publié dans Br J Pharmacol (2019)

The hybrid pyrroloisoindolone-dehydropyrrolizine alkaloid (-)-chlorizidine A targets proteins within the glycolytic pathway

par Álvarez-Micó, Xavier, Rocha, Danilo D., Guimarães, Larissa A., Ambrose, Andrew, Chapman, Eli, Costa-Lotufo, Leticia V., La Clair, James J., Fenical, William
Publié dans Chembiochem (2015)

Palyosulfonoceramides A and B: Unique Sulfonylated Ceramides from the Brazilian Zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis

par Almeida, Jose Gustavo L., Maia, Ana Isabel V., Wilke, Diego V., Silveira, Edilberto R., Braz-Filho, Raimundo, La Clair, James J., Costa-Lotufo, Leticia V., Pessoa, Otília Deusdenia L.
Publié 2012

Metabolomic Fingerprinting of Salinispora From Atlantic Oceanic Islands

par Bauermeister, Anelize, Velasco-Alzate, Karen, Dias, Tiago, Macedo, Helena, Ferreira, Elthon G., Jimenez, Paula C., Lotufo, Tito M. C., Lopes, Norberto P., Gaudêncio, Susana P., Costa-Lotufo, Letícia V.
Publié dans Front Microbiol (2018)

Marine Bacteria from Rocas Atoll as a Rich Source of Pharmacologically Active Compounds

par Velasco-Alzate, Karen Y., Bauermeister, Anelize, Tangerina, Marcelo M. P., Lotufo, Tito M. C., Ferreira, Marcelo J. P., Jimenez, Paula C., Padilla, Gabriel, Lopes, Norberto P., Costa-Lotufo, Letícia V.
Publié dans Mar Drugs (2019)

Multifunctional nanoemulsions for intraductal delivery as a new platform for local treatment of breast cancer

par Migotto, Amanda, Carvalho, Vanessa F. M., Salata, Giovanna C., da Silva, Fernanda W. M., Yan, Chao Yun Irene, Ishida, Kelly, Costa-Lotufo, Leticia V., Steiner, Alexandre A., Lopes, Luciana B.
Publié dans Drug Deliv (2018)

Botryane terpenoids produced by Nemania bipapillata, an endophytic fungus isolated from red alga Asparagopsis taxiformis - Falkenbergia stage

par Medina, Rebeca P., Araujo, Angela R., Batista, João M., Cardoso, Carmen L., Seidl, Cláudia, Vilela, Adriana F. L., Domingos, Helori V., Costa-Lotufo, Leticia V., Andersen, Raymond J., Silva, Dulce H. S.
Publié dans Sci Rep (2019)

Potent Cytotoxic Analogs of Amphidinolides from the Atlantic Octocoral Stragulum bicolor

par Nuzzo, Genoveffa, Gomes, Bruno de Araújo, Gallo, Carmela, Amodeo, Pietro, Sansone, Clementina, Pessoa, Otília D. L., Manzo, Emiliano, Vitale, Rosa Maria, Ianora, Adrianna, Santos, Evelyne A., Costa-Lotufo, Leticia V., Fontana, Angelo
Publié dans Mar Drugs (2019)

ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A

par Tillotson, Joseph, Kedzior, Magdalena, Guimarães, Larissa, Ross, Alison B., Peters, Tara L., Ambrose, Andrew J., Schmidlin, Cody J., Zhang, Donna D., Costa-Lotufo, Letícia V., Rodríguez, Abimael D., Schatz, Jonathan H., Chapman, Eli
Publié dans Bioorg Med Chem Lett (2017)

Metabolomic study of marine Streptomyces sp.: Secondary metabolites and the production of potential anticancer compounds

par Tangerina, Marcelo M. P., Furtado, Luciana Costa, Leite, Vida M. B., Bauermeister, Anelize, Velasco-Alzate, Karen, Jimenez, Paula C., Garrido, Leandro M., Padilla, Gabriel, Lopes, Norberto P., Costa-Lotufo, Leticia V., Pena Ferreira, Marcelo J.
Publié dans PLoS One (2020)

Ritterostatin G(N)1(N), a Cephalostatin-Ritterazine bis-Steroidal Pyrazine Hybrid, Selectively Targets GRP78**

par Ambrose, Andrew J., Santos, Evelyne A., Jimenez, Paula C., Rocha, Danilo D., Wilke, Diego V., Beuzer, Paolo, Axelrod, Josh, Kanduluru, Ananda Kumar, Fuchs, Philip L., Cang, Hu, Costa-Lotufo, Letícia V., Chapman, Eli, La Clair, James J.
Publié dans Chembiochem (2017)

Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins

par Sahm, Bianca Del B., Peres, Jade, Rezende-Teixeira, Paula, Santos, Evelyne A., Branco, Paola C., Bauermeister, Anelize, Kimani, Serah, Moreira, Eduarda A., Bisi-Alves, Renata, Bellis, Claire, Mlaza, Mihlali, Jimenez, Paula C., Lopes, Norberto P., Machado-Santelli, Glaucia M., Prince, Sharon, Costa-Lotufo, Leticia V.
Publié dans Front Chem (2020)

A community resource for paired genomic and metabolomic data mining

par Schorn, Michelle A., Verhoeven, Stefan, Ridder, Lars, Huber, Florian, Acharya, Deepa D., Aksenov, Alexander A., Aleti, Gajender, Moghaddam, Jamshid Amiri, Aron, Allegra T., Aziz, Saefuddin, Bauermeister, Anelize, Bauman, Katherine D., Baunach, Martin, Beemelmanns, Christine, Beman, J. Michael, Berlanga-Clavero, María Victoria, Blacutt, Alex A., Bode, Helge B., Boullie, Anne, Brejnrod, Asker, Bugni, Tim S., Calteau, Alexandra, Cao, Liu, Carrión, Víctor J., Castelo-Branco, Raquel, Chanana, Shaurya, Chase, Alexander B., Chevrette, Marc G., Costa-Lotufo, Leticia V., Crawford, Jason M., Currie, Cameron R., Cuypers, Bart, Dang, Tam, de Rond, Tristan, Demko, Alyssa M., Dittmann, Elke, Du, Chao, Drozd, Christopher, Dujardin, Jean-Claude, Dutton, Rachel J., Edlund, Anna, Fewer, David P., Garg, Neha, Gauglitz, Julia M., Gentry, Emily C., Gerwick, Lena, Glukhov, Evgenia, Gross, Harald, Gugger, Muriel, Guillén Matus, Dulce G., Helfrich, Eric J. N., Hempel, Benjamin-Florian, Hur, Jae-Seoun, Iorio, Marianna, Jensen, Paul R., Kang, Kyo Bin, Kaysser, Leonard, Kelleher, Neil L., Kim, Chung Sub, Kim, Ki Hyun, Koester, Irina, König, Gabriele M., Leao, Tiago, Lee, Seoung Rak, Lee, Yi-Yuan, Li, Xuanji, Little, Jessica C., Maloney, Katherine N., Männle, Daniel, Martin H., Christian, McAvoy, Andrew C., Metcalf, Willam W., Mohimani, Hosein, Molina-Santiago, Carlos, Moore, Bradley S., Mullowney, Michael W., Muskat, Mitchell, Nothias, Louis-Félix, O’Neill, Ellis C., Parkinson, Elizabeth I., Petras, Daniel, Piel, Jörn, Pierce, Emily C., Pires, Karine, Reher, Raphael, Romero, Diego, Roper, M. Caroline, Rust, Michael, Saad, Hamada, Saenz, Carmen, Sanchez, Laura M., Sørensen, Søren Johannes, Sosio, Margherita, Süssmuth, Roderich D., Sweeney, Douglas, Tahlan, Kapil, Thomson, Regan J., Tobias, Nicholas J., Trindade-Silva, Amaro E., van Wezel, Gilles P., Wang, Mingxun, Weldon, Kelly C., Zhang, Fan, Ziemert, Nadine, Duncan, Katherine R., Crüsemann, Max, Rogers, Simon, Dorrestein, Pieter C., Medema, Marnix H., van der Hooft, Justin J. J.
Publié dans Nat Chem Biol (2021)