Ritterostatin G(N)1(N), a Cephalostatin-Ritterazine bis-Steroidal Pyrazine Hybrid, Selectively Targets GRP78**

Natural products discovered using agnostic approaches, unlike rationally designed or HTS obtained leads, offer the ability to reveal new biological pathways, and hence, serve as an important vehicle to unveil new avenues in drug discovery. The ritterazine-cephalostatin family of natural products dis...

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Vydáno v:Chembiochem
Hlavní autoři: Ambrose, Andrew J., Santos, Evelyne A., Jimenez, Paula C., Rocha, Danilo D., Wilke, Diego V., Beuzer, Paolo, Axelrod, Josh, Kanduluru, Ananda Kumar, Fuchs, Philip L., Cang, Hu, Costa-Lotufo, Letícia V., Chapman, Eli, La Clair, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562448/
https://ncbi.nlm.nih.gov/pubmed/28074539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600669
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