Ritterostatin G(N)1(N), a Cephalostatin-Ritterazine bis-Steroidal Pyrazine Hybrid, Selectively Targets GRP78**

Natural products discovered using agnostic approaches, unlike rationally designed or HTS obtained leads, offer the ability to reveal new biological pathways, and hence, serve as an important vehicle to unveil new avenues in drug discovery. The ritterazine-cephalostatin family of natural products dis...

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Détails bibliographiques
Publié dans:Chembiochem
Auteurs principaux: Ambrose, Andrew J., Santos, Evelyne A., Jimenez, Paula C., Rocha, Danilo D., Wilke, Diego V., Beuzer, Paolo, Axelrod, Josh, Kanduluru, Ananda Kumar, Fuchs, Philip L., Cang, Hu, Costa-Lotufo, Letícia V., Chapman, Eli, La Clair, James J.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562448/
https://ncbi.nlm.nih.gov/pubmed/28074539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600669
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