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The hybrid pyrroloisoindolone-dehydropyrrolizine alkaloid (-)-chlorizidine A targets proteins within the glycolytic pathway
The cytotoxic activity of (-)-chlorizidine A, a marine alkaloid containing a unique fusion between a pyrroloisoindolone and dehydropyrrolizine, was explored using a combination of cellular and molecular methods. Our studies began by applying preliminary SAR evidence gathered from semisynthetic bioac...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835225/ https://ncbi.nlm.nih.gov/pubmed/26267855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500229 |
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