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Chlorizidine, A Cytotoxic 5H-Pyrrolo[2,1-a]isoindol-5-one-Containing Alkaloid from a Marine Streptomyces sp
[Image: see text] Cultivation of an obligate marine Streptomyces strain has provided the cytotoxic natural product chlorizidine. X-Ray crystallographic analysis revealed that the metabolite is composed of a chlorinated 2,3-dihydropyrrolizine ring attached to a chlorinated 5H-pyrrolo[2,1-a]isoindol-5...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702164/ https://ncbi.nlm.nih.gov/pubmed/23405849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol303374e |
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