Progress toward Fulfilling the Potential of Immunomodulation in Childhood Neurodegeneration?

Autor Cooper, Jonathan D., Nelvagal, Hemanth R.
Vydáno v Mol Ther (2017)

Pathogenesis and Therapies for Infantile Neuronal Ceroid Lipofuscinosis (infantile CLN1 disease)

Autor Hawkins-Salsbury, Jacqueline A., Cooper, Jonathan D., Sands, Mark S.
Vydáno v Biochim Biophys Acta (2013)

Selectivity and Types of Cell Death in the Neuronal Ceroid Lipofuscinoses (NCLs)

Autor Mitchison, Hannah M., Lim, Ming J., Cooper, Jonathan D.
Vydáno v Brain Pathol (2006)

Anti-Inflammatory Impact of Minocycline in a Mouse Model of Tauopathy

Autor Garwood, Claire J., Cooper, Jonathan D., Hanger, Diane P., Noble, Wendy
Vydáno 2010

Activation of Non‐neuronal Cells within the Prenatal Developing Brain of Sheep with Neuronal Ceroid Lipofuscinosis

Autor Kay, Graham W., Palmer, David N., Rezaie, Payam, Cooper, Jonathan D.
Vydáno v Brain Pathol (2006)

Hippocampal Pathology in the Human Neuronal Ceroid‐Lipofuscinoses: Distinct Patterns of Storage Deposition, Neurodegeneration and Glial Activation

Autor Tyynelä, Jaana, Cooper, Jonathan D, Khan, M Nadeem, Shemilt, Stephen JA, Haltia, Matti
Vydáno v Brain Pathol (2006)

Apparent Loss and Hypertrophy of Interneurons in a Mouse Model of Neuronal Ceroid Lipofuscinosis: Evidence for Partial Response to Insulin-Like Growth Factor-1 Treatment

Autor Cooper, Jonathan D., Messer, Anne, Feng, Andrew K., Chua-Couzens, Jane, Mobley, William C.
Vydáno v J Neurosci (1999)

Location and connectivity determine GABAergic interneuron survival in the brains of South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis

Autor Oswald, Manfred J, Palmer, David N, Kay, Graham W, Barwell, Karen J, Cooper, Jonathan D
Vydáno 2008

Cerebellar Pathology and Motor Deficits in the Palmitoyl Protein Thioesterase 1-Deficient Mouse

Autor Macauley, Shannon L., Wozniak, David F., Kielar, Catherine, Tan, Yun, Cooper, Jonathan D., Sands, Mark S.
Vydáno 2009

Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease

Autor Kovács, Attila D., Saje, Angelika, Wong, Andrew, Ramji, Serena, Cooper, Jonathan D., Pearce, David A.
Vydáno 2012

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease)

Autor Wager, Kim, Zdebik, Anselm A., Fu, Sonia, Cooper, Jonathan D., Harvey, Robert J., Russell, Claire
Vydáno v PLoS One (2016)

Enhanced expression of manganese-dependent superoxide dismutase in human and sheep CLN6 tissues.

Autor Heine, Claudia, Tyynelä, Jaana, Cooper, Jonathan D, Palmer, David N, Elleder, Milan, Kohlschütter, Alfried, Braulke, Thomas
Vydáno 2003

Early glial activation, synaptic changes and axonal pathology in the thalamocortical system of Niemann–Pick type C1 mice

Autor Pressey, Sarah N.R., Smith, David A., Wong, Andrew M.S., Platt, Frances M., Cooper, Jonathan D.
Vydáno 2012

A Murine Model of Variant Late Infantile Ceroid Lipofuscinosis Recapitulates Behavioral and Pathological Phenotypes of Human Disease

Autor Morgan, Jeremy P., Magee, Helen, Wong, Andrew, Nelson, Tarah, Koch, Bettina, Cooper, Jonathan D., Weimer, Jill M.
Vydáno 2013

Combination small molecule PPT1 mimetic and CNS-directed gene therapy as a treatment for infantile neuronal ceroid lipofuscinosis

Autor Roberts, Marie S., Macauley, Shannon L., Wong, Andrew M., Yilmas, Denis, Hohm, Sarah, Cooper, Jonathan D., Sands, Mark S.
Vydáno 2012

Synergistic effects of treating the spinal cord and brain in CLN1 disease

Autor Shyng, Charles, Nelvagal, Hemanth R., Dearborn, Joshua T., Tyynelä, Jaana, Schmidt, Robert E., Sands, Mark S., Cooper, Jonathan D.
Vydáno v Proc Natl Acad Sci U S A (2017)

Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases

Autor von Schantz, Carina, Saharinen, Juha, Kopra, Outi, Cooper, Jonathan D, Gentile, Massimiliano, Hovatta, Iiris, Peltonen, Leena, Jalanko, Anu
Vydáno 2008

Synergistic effects of CNS-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis

Autor Macauley, Shannon L., Roberts, Marie S., Wong, Andrew M., McSloy, Francesca, Reddy, Adarsh S., Cooper, Jonathan D., Sands, Mark S.
Vydáno 2012

Correction: Disruption of the Autophagy-Lysosome Pathway Is Involved in Neuropathology of the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis

Autor Thelen, Melanie, Damme, Markus, Schweizer, Michaela, Hagel, Christian, Wong, Andrew M.S., Cooper, Jonathan D., Braulke, Thomas, Galliciotti, Giovanna
Vydáno 2012

Evolution of structural abnormalities in the rat brain following in utero exposure to maternal immune activation: A longitudinal in vivo MRI study

Autor Crum, William R., Sawiak, Stephen J., Chege, Winfred, Cooper, Jonathan D., Williams, Steven C.R., Vernon, Anthony C.
Vydáno v Brain Behav Immun (2017)