Location and connectivity determine GABAergic interneuron survival in the brains of South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis

The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are fatal inherited neurodegenerative diseases. Sheep affected with the CLN6 form provide a valuable model to investigate underlying disease mechanisms from preclinical stages. Excitatory neuron loss in these sheep is markedly regional, local...

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Hlavní autoři: Oswald, Manfred J, Palmer, David N, Kay, Graham W, Barwell, Karen J, Cooper, Jonathan D
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647510/
https://ncbi.nlm.nih.gov/pubmed/18634879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.06.004
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