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Location and connectivity determine GABAergic interneuron survival in the brains of South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis

The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are fatal inherited neurodegenerative diseases. Sheep affected with the CLN6 form provide a valuable model to investigate underlying disease mechanisms from preclinical stages. Excitatory neuron loss in these sheep is markedly regional, local...

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Bibliografiske detaljer
Main Authors: Oswald, Manfred J, Palmer, David N, Kay, Graham W, Barwell, Karen J, Cooper, Jonathan D
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647510/
https://ncbi.nlm.nih.gov/pubmed/18634879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.06.004
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