Angiogenesis Inhibitors – Current Strategies and Future Prospects

Por Cook, Kristina M., Figg, William D.
Publicado em 2010

Allosteric Control of βII-Tryptase by a Redox Active Disulfide Bond

Por Cook, Kristina M., McNeil, H. Patrick, Hogg, Philip J.
Publicado em 2013

Control of blood proteins by functional disulfide bonds

Por Butera, Diego, Cook, Kristina M., Chiu, Joyce, Wong, Jason W. H., Hogg, Philip J.
Publicado em 2014

Epidithiodiketopiperazines Block the Interaction between Hypoxia-inducible Factor-1α (HIF-1α) and p300 by a Zinc Ejection Mechanism

Por Cook, Kristina M., Hilton, Stephen T., Mecinović, Jasmin, Motherwell, William B., Figg, William D., Schofield, Christopher J.
Publicado em 2009

Zinc is a potent and specific inhibitor of IFN-λ3 signalling

Por Read, Scott A., O'Connor, Kate S., Suppiah, Vijay, Ahlenstiel, Chantelle L. E., Obeid, Stephanie, Cook, Kristina M., Cunningham, Anthony, Douglas, Mark W., Hogg, Philip J., Booth, David, George, Jacob, Ahlenstiel, Golo
Publicado no Nat Commun (2017)

Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer

Por Reece, Kelie M, Richardson, Emily D, Cook, Kristina M, Campbell, Tessa J, Pisle, Stephen T, Holly, Alesia J, Venzon, David J, Liewehr, David J, Chau, Cindy H, Price, Douglas K, Figg, William D
Publicado em 2014

A substrate-driven allosteric switch that enhances PDI catalytic activity

Por Bekendam, Roelof H., Bendapudi, Pavan K., Lin, Lin, Nag, Partha P., Pu, Jun, Kennedy, Daniel R., Feldenzer, Alexandra, Chiu, Joyce, Cook, Kristina M., Furie, Bruce, Huang, Mingdong, Hogg, Philip J., Flaumenhaft, Robert
Publicado no Nat Commun (2016)

Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

Por Harris, Emily M., Strope, Jonathan D., Beedie, Shaunna L., Huang, Phoebe A., Goey, Andrew K. L., Cook, Kristina M., Schofield, Christopher J., Chau, Cindy H., Cadelis, Melissa M., Copp, Brent R., Gustafson, Kirk R., Figg, William D.
Publicado no Mar Drugs (2018)

Autoregulation of von Willebrand factor function by a disulfide bond switch

Por Butera, Diego, Passam, Freda, Ju, Lining, Cook, Kristina M., Woon, Heng, Aponte-Santamaría, Camilo, Gardiner, Elizabeth, Davis, Amanda K., Murphy, Deirdre A., Bronowska, Agnieszka, Luken, Brenda M., Baldauf, Carsten, Jackson, Shaun, Andrews, Robert, Gräter, Frauke, Hogg, Philip J.
Publicado no Sci Adv (2018)

Inhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II)

Por Jayatunga, Madura K. P., Thompson, Sam, McKee, Tawnya C., Chan, Mun Chiang, Reece, Kelie M., Hardy, Adam P., Sekirnik, Rok, Seden, Peter T., Cook, Kristina M., McMahon, James B., Figg, William D., Schofield, Christopher J., Hamilton, Andrew D.
Publicado no Eur J Med Chem (2014)