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Zinc is a potent and specific inhibitor of IFN-λ3 signalling

Lambda interferons (IFNL, IFN-λ) are pro-inflammatory cytokines important in acute and chronic viral infection. Single-nucleotide polymorphisms rs12979860 and rs8099917 within the IFNL gene locus predict hepatitis C virus (HCV) clearance, as well as inflammation and fibrosis progression in viral and...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Read, Scott A., O'Connor, Kate S., Suppiah, Vijay, Ahlenstiel, Chantelle L. E., Obeid, Stephanie, Cook, Kristina M., Cunningham, Anthony, Douglas, Mark W., Hogg, Philip J., Booth, David, George, Jacob, Ahlenstiel, Golo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442324/
https://ncbi.nlm.nih.gov/pubmed/28513591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15245
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