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Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models
Elements of the hypoxia inducible factor (HIF) transcriptional system, a key regulator of the cellular hypoxic response, are up-regulated in a range of cancer cells. HIF is fundamentally involved in tumor angiogenesis, invasion, and energy metabolism. Inhibition of the transcriptional activity of HI...
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Publicado no: | Mar Drugs |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071056/ https://ncbi.nlm.nih.gov/pubmed/30029505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16070241 |
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