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Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models
Elements of the hypoxia inducible factor (HIF) transcriptional system, a key regulator of the cellular hypoxic response, are up-regulated in a range of cancer cells. HIF is fundamentally involved in tumor angiogenesis, invasion, and energy metabolism. Inhibition of the transcriptional activity of HI...
Enregistré dans:
| Publié dans: | Mar Drugs |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071056/ https://ncbi.nlm.nih.gov/pubmed/30029505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16070241 |
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