Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

Elements of the hypoxia inducible factor (HIF) transcriptional system, a key regulator of the cellular hypoxic response, are up-regulated in a range of cancer cells. HIF is fundamentally involved in tumor angiogenesis, invasion, and energy metabolism. Inhibition of the transcriptional activity of HI...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mar Drugs
Auteurs principaux: Harris, Emily M., Strope, Jonathan D., Beedie, Shaunna L., Huang, Phoebe A., Goey, Andrew K. L., Cook, Kristina M., Schofield, Christopher J., Chau, Cindy H., Cadelis, Melissa M., Copp, Brent R., Gustafson, Kirk R., Figg, William D.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071056/
https://ncbi.nlm.nih.gov/pubmed/30029505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16070241
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