PLP-Dependent Enzymes

Por Paiardini, Alessandro, Contestabile, Roberto, Buckle, Ashley M., Cellini, Barbara
Publicado em 2014

The mechanism of addition of pyridoxal 5′-phosphate to Escherichia coli apo-serine hydroxymethyltransferase

Por Malerba, Francesca, Bellelli, Andrea, Giorgi, Alessandra, Bossa, Francesco, Contestabile, Roberto
Publicado em 2007

Crystal structure of glutamate-1-semialdehyde aminomutase: An α(2)-dimeric vitamin B(6)-dependent enzyme with asymmetry in structure and active site reactivity

Por Hennig, Michael, Grimm, Bernhard, Contestabile, Roberto, John, Robert A., Jansonius, Johan N.
Publicado em 1997

Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution

Por Campanini, Barbara, Bettati, Stefano, di Salvo, Martino Luigi, Mozzarelli, Andrea, Contestabile, Roberto
Publicado em 2013

A Bioinformatics Analysis Reveals a Group of MocR Bacterial Transcriptional Regulators Linked to a Family of Genes Coding for Membrane Proteins

Por Milano, Teresa, Angelaccio, Sebastiana, Tramonti, Angela, Di Salvo, Martino Luigi, Contestabile, Roberto, Pascarella, Stefano
Publicado no Biochem Res Int (2016)

Data from computational analysis of the peptide linkers in the MocR bacterial transcriptional regulators

Por Angelaccio, Sebastiana, Milano, Teresa, Tramonti, Angela, Di Salvo, Martino Luigi, Contestabile, Roberto, Pascarella, Stefano
Publicado no Data Brief (2016)

Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction

Por Di Salvo, Martino L., Scarsdale, J. Neel, Kazanina, Galina, Contestabile, Roberto, Schirch, Verne, Wright, H. Tonie
Publicado em 2013

Molecular Basis of Reduced Pyridoxine 5′-Phosphate Oxidase Catalytic Activity in Neonatal Epileptic Encephalopathy Disorder

Por Musayev, Faik N., Di Salvo, Martino L., Saavedra, Mario A., Contestabile, Roberto, Ghatge, Mohini S., Haynes, Alexina, Schirch, Verne, Safo, Martin K.
Publicado em 2009

ON THE CATALYTIC MECHANISM AND STEREOSPECIFICITY OF ESCHERICHIA COLI l-THREONINE ALDOLASE

Por di Salvo, Martino L., Remesh, Soumya G., Vivoli, Mirella, Ghatge, Mohini S., Paiardini, Alessandro, D’Aguanno, Simona, Safo, Martin K., Contestabile, Roberto
Publicado no FEBS J (2013)

Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis

Por Mkrtchyan, Garik, Aleshin, Vasily, Parkhomenko, Yulia, Kaehne, Thilo, Luigi Di Salvo, Martino, Parroni, Alessia, Contestabile, Roberto, Vovk, Andrey, Bettendorff, Lucien, Bunik, Victoria
Publicado no Sci Rep (2015)

Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

Por Gandhi, Amit K., Desai, Jigar V., Ghatge, Mohini S., di Salvo, Martino L., Di Biase, Stefano, Danso-Danquah, Richmond, Musayev, Faik N., Contestabile, Roberto, Schirch, Verne, Safo, Martin K.
Publicado em 2012

Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase

Por Ghatge, Mohini S., Contestabile, Roberto, di Salvo, Martino L., Desai, Jigar V., Gandhi, Amit K., Camara, Christina M., Florio, Rita, González, Isabel N., Parroni, Alessia, Schirch, Verne, Safo, Martin K.
Publicado em 2012

Molecular Basis of E. coli L-Threonine Aldolase Catalytic Inactivation at Low pH

Por Remesh, Soumya G., Ghatge, Mohini S., Ahmed, Mostafa H., Musayev, Faik N., Gandhi, Amit, Chowdhury, Nadia, di Salvo, Martino L., Kellogg, Glen E., Contestabile, Roberto, Schirch, Verne, Safo, Martin K.
Publicado no Biochim Biophys Acta (2015)

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells

Por Marani, Marina, Paone, Alessio, Fiascarelli, Alessio, Macone, Alberto, Gargano, Maurizio, Rinaldo, Serena, Giardina, Giorgio, Pontecorvi, Valentino, Koes, David, McDermott, Lee, Yang, Tianyi, Paiardini, Alessandro, Contestabile, Roberto, Cutruzzolà, Francesca
Publicado no Oncotarget (2015)