Molecular Basis of Reduced Pyridoxine 5′-Phosphate Oxidase Catalytic Activity in Neonatal Epileptic Encephalopathy Disorder

Mutations in pyridoxine 5′-phosphate oxidase are known to cause neonatal epileptic encephalopathy. This disorder has no cure or effective treatment and is often fatal. Pyridoxine 5′-phosphate oxidase catalyzes the oxidation of pyridoxine 5′-phosphate to pyridoxal 5′-phosphate, the active cofactor fo...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Musayev, Faik N., Di Salvo, Martino L., Saavedra, Mario A., Contestabile, Roberto, Ghatge, Mohini S., Haynes, Alexina, Schirch, Verne, Safo, Martin K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781495/
https://ncbi.nlm.nih.gov/pubmed/19759001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038372
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items