Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

Several drugs and natural compounds are known to be highly neurotoxic, triggering epileptic convulsions or seizures, and causing headaches, agitations, as well as other neuronal symptoms. The neurotoxic effects of some of these compounds, including theophylline and ginkgotoxin, have been traced to t...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Gandhi, Amit K., Desai, Jigar V., Ghatge, Mohini S., di Salvo, Martino L., Di Biase, Stefano, Danso-Danquah, Richmond, Musayev, Faik N., Contestabile, Roberto, Schirch, Verne, Safo, Martin K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412620/
https://ncbi.nlm.nih.gov/pubmed/22879864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040954
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