Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance

por Handzlik, Michal K., Constantin‐Teodosiu, Dumitru, Greenhaff, Paul L., Cole, Mark A.
Publicado en J Physiol (2018)

Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia

por Handzlik, Michal K., Tooth, David J., Constantin-Teodosiu, Dumitru, Greenhaff, Paul L., Cole, Mark A.
Publicado en Biosci Rep (2021)

First-pass perfusion CMR two days after infarction predicts severity of functional impairment six weeks later in the rat heart

por Stuckey, Daniel J, Carr, Carolyn A, Meader, Stephanie J, Tyler, Damian J, Cole, Mark A, Clarke, Kieran
Publicado 2011

Isoproterenol-induced changes in perfusion, function, energy metabolism and nitric oxide pathway: in vivo and ex vivo study in the rat heart

por Desrois, Martine, Kober, Frank, Lan, Carole, Dalmasso, Christiane, Cole, Mark A, Clarke, Kieran, Cozzone, Patrick J, Bernard, Monique
Publicado 2011

Changes in Cardiac Substrate Transporters and Metabolic Proteins Mirror the Metabolic Shift in Patients with Aortic Stenosis

por Heather, Lisa C., Howell, Neil J., Emmanuel, Yaso, Cole, Mark A., Frenneaux, Michael P., Pagano, Domenico, Clarke, Kieran
Publicado 2011

Ongoing Dual-Angle Measurements for the Correction of Partial Saturation in (31)P MR Spectroscopy

por Tyler, Damian J., Lopez, Orlando, Cole, Mark A., Carr, Carolyn A., Stuckey, Daniel J., Lakatta, Edward, Clarke, Kieran, Spencer, Richard G.
Publicado 2010

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin

por Mansor, Latt S, Gonzalez, Eileen R, Cole, Mark A, Tyler, Damian J, Beeson, Jessica H, Clarke, Kieran, Carr, Carolyn A, Heather, Lisa C
Publicado 2013

Real-time assessment of Krebs cycle metabolism using hyperpolarized (13)C magnetic resonance spectroscopy

por Schroeder, Marie A., Atherton, Helen J., Ball, Daniel R., Cole, Mark A., Heather, Lisa C., Griffin, Julian L., Clarke, Kieran, Radda, George K., Tyler, Damian J.
Publicado 2009

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

por Cole, Mark A., Murray, Andrew J., Cochlin, Lowri E., Heather, Lisa C., McAleese, Sara, Knight, Nicholas S., Sutton, Elizabeth, Jamil, Amira Abd, Parassol, Nadege, Clarke, Kieran
Publicado 2011

Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

por Mansor, Latt S., Mehta, Keshavi, Aksentijevic, Dunja, Carr, Carolyn A., Lund, Trine, Cole, Mark A., Page, Lydia Le, Sousa Fialho, Maria da Luz, Shattock, Michael J., Aasum, Ellen, Clarke, Kieran, Tyler, Damian J, Heather, Lisa C.
Publicado en J Physiol (2015)

On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury

por Cole, Mark A., Abd Jamil, Amira H., Heather, Lisa C., Murray, Andrew J., Sutton, Elizabeth R., Slingo, Mary, Sebag-Montefiore, Liam, Tan, Suat Cheng, Aksentijević, Dunja, Gildea, Ottilie S., Stuckey, Daniel J., Yeoh, Kar Kheng, Carr, Carolyn A., Evans, Rhys D., Aasum, Ellen, Schofield, Christopher J., Ratcliffe, Peter J., Neubauer, Stefan, Robbins, Peter A., Clarke, Kieran
Publicado en FASEB J (2016)

Novel ketone diet enhances physical and cognitive performance

por Murray, Andrew J., Knight, Nicholas S., Cole, Mark A., Cochlin, Lowri E., Carter, Emma, Tchabanenko, Kirill, Pichulik, Tica, Gulston, Melanie K., Atherton, Helen J., Schroeder, Marie A., Deacon, Robert M. J., Kashiwaya, Yoshihiro, King, M. Todd, Pawlosky, Robert, Rawlins, J. Nicholas P., Tyler, Damian J., Griffin, Julian L., Robertson, Jeremy, Veech, Richard L., Clarke, Kieran
Publicado en FASEB J (2016)