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Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
KEY POINTS: The cardiac metabolic reprogramming seen in heart diseases such as myocardial infarction and hypertrophy shares similarities with that seen in chronic hypoxia, but understanding of how the hypoxic heart responds to further hypoxic challenge – hypoxic tolerance – is limited. The pyruvate...
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| Publicado no: | J Physiol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6068244/ https://ncbi.nlm.nih.gov/pubmed/29383727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275357 |
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