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PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation

The mechanisms behind the reduction in muscle pyruvate dehydrogenase complex (PDC)-controlled carbohydrate (CHO) oxidation during chronic high-fat dietary intake are poorly understood, as is the basis of CHO oxidation restoration during muscle contraction. C2C12 myotubes were treated with (300 μM) p...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chien, Hung-Che, Greenhaff, Paul L., Constantin-Teodosiu, Dumitru
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460628/
https://ncbi.nlm.nih.gov/pubmed/32824862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165942
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