Synthesis of α-Halo-α,α-Difluoromethyl Ketones by a Trifluoroacetate Release/Halogenation Protocol

Autor John, Jinu P., Colby, David A.
Vydáno 2011

Proposed Actions for the US Food and Drug Administration to Implement to Minimize Adverse Effects Associated With Energy Drink Consumption

Autor Thorlton, Janet, Colby, David A., Devine, Paige
Vydáno 2014

Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine: Total Synthesis of (+)- and ent-(−)-Vinblastine

Autor Ishikawa, Hayato, Colby, David A., Boger, Dale L.
Vydáno 2008

Synthesis of β-Fluoro-α,β-Unsaturated Amides from the Fragmentation of Morpholine 3,3,3-Trifluoropropanamide by Grignard Reagents

Autor Adam, Amna T., Fronczek, Frank R., Colby, David A.
Vydáno v Org Lett (2020)

Optimized Synthesis of a Pentafluoro-gem-diol and Conversion to a CF(2)Br-Glucopyranose through Trifluoroacetate-Release and Halogenation

Autor Hazlitt, Robert A., John, Jinu P., Tran, Que-Lynn, Colby, David A.
Vydáno v Tetrahedron Lett (2016)

Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles

Autor Barrios, Francis J., Springer, Brannon C., Hazlitt, Robert A., Colby, David A.
Vydáno v Synthesis (Stuttg) (2014)

Generation of Magnesium Pentafluoropropen-2-olate from Hexafluoroisopropanol and Synthesis of 2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones

Autor Hazlitt, Robert A., Tran, Que-Lynn, Sowaileh, Munia F., Colby, David A.
Vydáno v J Org Chem (2017)

Synthesis, biological evaluation, and NMR studies of 3-fluorinated derivatives of 3’,4’,5’-trihydroxyflavone and 3’,4’,5’-trimethoxyflavone

Autor Alshammari, Maali D., Kucheryavy, Pavel V., Ashpole, Nicole M., Colby, David A.
Vydáno v Bioorg Med Chem Lett (2020)

Fluorinated Amino-Derivatives of the Sesquiterpene Lactone, Parthenolide, as (19)F NMR Probes in Deuterium-Free Environments

Autor Woods, James R., Mo, Huaping, Bieberich, Andrew A., Alavanja, Tanja, Colby, David A.
Vydáno 2011

Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators

Autor Brown, Katie M., Roy, Kuldeep K., Hockerman, Gregory H., Doerksen, Robert J., Colby, David A.
Vydáno v J Med Chem (2015)

Conversion of Methyl Ketones and Methyl Sulfones into α-Deutero-α,α-Difluoromethyl Ketones and α-Deutero-α,α-Difluoromethyl Sulfones in Three Synthetic Steps

Autor Sowaileh, Munia F., Han, Changho, Hazlitt, Robert A., Kim, Eun Hoo, John, Jinu P., Colby, David A.
Vydáno v Tetrahedron Lett (2016)

Magnesium-promoted Additions of Difluoroenolates to Unactivated Imines

Autor Nguyen, Alex L., Khatri, Hari R., Woods, James R., Baldwin, Cassidy S., Fronczek, Frank R., Colby, David A.
Vydáno v J Org Chem (2018)

Controlling the Cleavage of Carbon–Carbon Bonds to Generate α,α-Difluorobenzyl Carbanions for the Construction of Difluoromethylbenzenes

Autor Khatri, Hari R., Han, Changho, Luong, Erica, Pan, Xiaoliang, Adam, Amna T., Alshammari, Maali D., Shao, Yihan, Colby, David A.
Vydáno v J Org Chem (2019)

Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR

Autor Woods, James R., Riofski, Mark V., Zheng, Mary M., O'Banion, Melissa A., Mo, Huaping, Kirshner, Julia, Colby, David A.
Vydáno 2013

Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

Autor Ishikawa, Hayato, Colby, David A., Seto, Shigeki, Va, Porino, Tam, Annie, Kakei, Hiroyuki, Rayl, Thomas J., Hwang, Inkyu, Boger, Dale L.
Vydáno 2009

A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra

Autor Glauber, Kristine M., Dana, Catherine E., Park, Steve S., Colby, David A., Noro, Yukihiko, Fujisawa, Toshitaka, Chamberlin, A. Richard, Steele, Robert E.
Vydáno 2013

A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra

Autor Glauber, Kristine M., Dana, Catherine E., Park, Steve S., Colby, David A., Noro, Yukihiko, Fujisawa, Toshitaka, Chamberlin, A. Richard, Steele, Robert E.
Vydáno v Development (2015)

Agonists of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor Derived from β-Hydroxy and β-Amino Difluoromethyl Ketones

Autor Sowaileh, Munia F., Salyer, Amy E., Roy, Kuldeep K., John, Jinu P., Woods, James R., Doerksen, Robert J., Hockerman, Gregory H., Colby, David A.
Vydáno v Bioorg Med Chem Lett (2018)

Total Synthesis and Evaluation of Cytostatin, its C10–C11 Diastereomers, and Additional Key Analogues: Impact on PP2A Inhibition

Autor Lawhorn, Brian G., Boga, Sobhana B., Wolkenberg, Scott E., Colby, David A., Gauss, Carla-Maria, Swingle, Mark R., Amable, Lauren, Honkanen, Richard E., Boger, Dale L.
Vydáno 2006

15-Methylene-Eburnamonine Kills Leukemic Stem Cells and Reduces Engraftment in a Humanized Bone Marrow Xenograft Mouse Model of Leukemia

Autor Gunasekara, Dilini C., Zheng, Mary M., Mojtahed, Tara, Woods, James R., Fandy, Tamer E., Riofski, Mark V., Glackin, Carlotta A., Hassan, Hazem E., Kirshner, Julia, Colby, David A.
Vydáno v ChemMedChem (2016)