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Magnesium-promoted Additions of Difluoroenolates to Unactivated Imines

Although there are many synthetic methods to produce fluorinated and trifluoromethylated organic structures, the construction of difluoromethylated compounds remains a synthetic challenge. We have discovered that using magnesium salts and organic bases, unactivated imines will react with difluoroeno...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Nguyen, Alex L., Khatri, Hari R., Woods, James R., Baldwin, Cassidy S., Fronczek, Frank R., Colby, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274396/
https://ncbi.nlm.nih.gov/pubmed/29446944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03014
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