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Chiral Magnesium BINOL Phosphate-Catalyzed Phosphination of Imines: Access to Enantioenriched α-Amino Phosphine Oxides

[Image: see text] A new method to synthesize chiral α-amino phosphine oxides is reported. The reaction combines N-substituted imines and diphenylphosphine oxide, and is catalyzed by a chiral magnesium phosphate salt. A wide variety of aliphatic and aromatic aldimines substituted by electron neutral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ingle, Gajendrasingh K., Liang, Yuxue, Mormino, Michael G., Li, Guilong, Fronczek, Frank R., Antilla, Jon C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115557/
https://ncbi.nlm.nih.gov/pubmed/21413695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200456y
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