Synthesis of α-Halo-α,α-Difluoromethyl Ketones by a Trifluoroacetate Release/Halogenation Protocol

av John, Jinu P., Colby, David A.
Publicerad 2011

Proposed Actions for the US Food and Drug Administration to Implement to Minimize Adverse Effects Associated With Energy Drink Consumption

av Thorlton, Janet, Colby, David A., Devine, Paige
Publicerad 2014

Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine: Total Synthesis of (+)- and ent-(−)-Vinblastine

av Ishikawa, Hayato, Colby, David A., Boger, Dale L.
Publicerad 2008

Synthesis of β-Fluoro-α,β-Unsaturated Amides from the Fragmentation of Morpholine 3,3,3-Trifluoropropanamide by Grignard Reagents

av Adam, Amna T., Fronczek, Frank R., Colby, David A.
I publikationen Org Lett (2020)

Optimized Synthesis of a Pentafluoro-gem-diol and Conversion to a CF(2)Br-Glucopyranose through Trifluoroacetate-Release and Halogenation

av Hazlitt, Robert A., John, Jinu P., Tran, Que-Lynn, Colby, David A.
I publikationen Tetrahedron Lett (2016)

Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles

av Barrios, Francis J., Springer, Brannon C., Hazlitt, Robert A., Colby, David A.
I publikationen Synthesis (Stuttg) (2014)

Generation of Magnesium Pentafluoropropen-2-olate from Hexafluoroisopropanol and Synthesis of 2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones

av Hazlitt, Robert A., Tran, Que-Lynn, Sowaileh, Munia F., Colby, David A.
I publikationen J Org Chem (2017)

Synthesis, biological evaluation, and NMR studies of 3-fluorinated derivatives of 3’,4’,5’-trihydroxyflavone and 3’,4’,5’-trimethoxyflavone

av Alshammari, Maali D., Kucheryavy, Pavel V., Ashpole, Nicole M., Colby, David A.
I publikationen Bioorg Med Chem Lett (2020)

Fluorinated Amino-Derivatives of the Sesquiterpene Lactone, Parthenolide, as (19)F NMR Probes in Deuterium-Free Environments

av Woods, James R., Mo, Huaping, Bieberich, Andrew A., Alavanja, Tanja, Colby, David A.
Publicerad 2011

Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators

av Brown, Katie M., Roy, Kuldeep K., Hockerman, Gregory H., Doerksen, Robert J., Colby, David A.
I publikationen J Med Chem (2015)

Conversion of Methyl Ketones and Methyl Sulfones into α-Deutero-α,α-Difluoromethyl Ketones and α-Deutero-α,α-Difluoromethyl Sulfones in Three Synthetic Steps

av Sowaileh, Munia F., Han, Changho, Hazlitt, Robert A., Kim, Eun Hoo, John, Jinu P., Colby, David A.
I publikationen Tetrahedron Lett (2016)

Magnesium-promoted Additions of Difluoroenolates to Unactivated Imines

av Nguyen, Alex L., Khatri, Hari R., Woods, James R., Baldwin, Cassidy S., Fronczek, Frank R., Colby, David A.
I publikationen J Org Chem (2018)

Controlling the Cleavage of Carbon–Carbon Bonds to Generate α,α-Difluorobenzyl Carbanions for the Construction of Difluoromethylbenzenes

av Khatri, Hari R., Han, Changho, Luong, Erica, Pan, Xiaoliang, Adam, Amna T., Alshammari, Maali D., Shao, Yihan, Colby, David A.
I publikationen J Org Chem (2019)

Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR

av Woods, James R., Riofski, Mark V., Zheng, Mary M., O'Banion, Melissa A., Mo, Huaping, Kirshner, Julia, Colby, David A.
Publicerad 2013

Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

av Ishikawa, Hayato, Colby, David A., Seto, Shigeki, Va, Porino, Tam, Annie, Kakei, Hiroyuki, Rayl, Thomas J., Hwang, Inkyu, Boger, Dale L.
Publicerad 2009

A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra

av Glauber, Kristine M., Dana, Catherine E., Park, Steve S., Colby, David A., Noro, Yukihiko, Fujisawa, Toshitaka, Chamberlin, A. Richard, Steele, Robert E.
Publicerad 2013

A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra

av Glauber, Kristine M., Dana, Catherine E., Park, Steve S., Colby, David A., Noro, Yukihiko, Fujisawa, Toshitaka, Chamberlin, A. Richard, Steele, Robert E.
I publikationen Development (2015)

Agonists of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor Derived from β-Hydroxy and β-Amino Difluoromethyl Ketones

av Sowaileh, Munia F., Salyer, Amy E., Roy, Kuldeep K., John, Jinu P., Woods, James R., Doerksen, Robert J., Hockerman, Gregory H., Colby, David A.
I publikationen Bioorg Med Chem Lett (2018)

Total Synthesis and Evaluation of Cytostatin, its C10–C11 Diastereomers, and Additional Key Analogues: Impact on PP2A Inhibition

av Lawhorn, Brian G., Boga, Sobhana B., Wolkenberg, Scott E., Colby, David A., Gauss, Carla-Maria, Swingle, Mark R., Amable, Lauren, Honkanen, Richard E., Boger, Dale L.
Publicerad 2006

15-Methylene-Eburnamonine Kills Leukemic Stem Cells and Reduces Engraftment in a Humanized Bone Marrow Xenograft Mouse Model of Leukemia

av Gunasekara, Dilini C., Zheng, Mary M., Mojtahed, Tara, Woods, James R., Fandy, Tamer E., Riofski, Mark V., Glackin, Carlotta A., Hassan, Hazem E., Kirshner, Julia, Colby, David A.
I publikationen ChemMedChem (2016)