iPS Cells for Modelling and Treatment of Retinal Diseases

Por Chen, Fred K., McLenachan, Samuel, Edel, Michael, Da Cruz, Lyndon, Coffey, Peter J., Mackey, David A.
Publicado no J Clin Med (2014)

Rapid and Efficient Directed Differentiation of Human Pluripotent Stem Cells Into Retinal Pigmented Epithelium

Por Buchholz, David E., Pennington, Britney O., Croze, Roxanne H., Hinman, Cassidy R., Coffey, Peter J., Clegg, Dennis O.
Publicado em 2013

Using induced pluripotent stems cells to understand retinal ciliopathy disease mechanisms and develop therapies

Por Parfitt, David A., Lane, Amelia, Ramsden, Conor, Jovanovic, Katarina, Coffey, Peter J., Hardcastle, Alison J., Cheetham, Michael E.
Publicado no Biochem Soc Trans (2016)

Stem cells in retinal regeneration: past, present and future

Por Ramsden, Conor M., Powner, Michael B., Carr, Amanda-Jayne F., Smart, Matthew J. K., da Cruz, Lyndon, Coffey, Peter J.
Publicado em 2013

ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium

Por Croze, Roxanne H., Buchholz, David E., Radeke, Monte J., Thi, William J., Hu, Qirui, Coffey, Peter J., Clegg, Dennis O.
Publicado em 2014

Using Stem Cells to Model Diseases of the Outer Retina

Por Yvon, Camille, Ramsden, Conor M., Lane, Amelia, Powner, Michael B., da Cruz, Lyndon, Coffey, Peter J., Carr, Amanda-Jayne F.
Publicado no Comput Struct Biotechnol J (2015)

Dissecting a Role for Melanopsin in Behavioural Light Aversion Reveals a Response Independent of Conventional Photoreception

Por Semo, Ma'ayan, Gias, Carlos, Ahmado, Ahmad, Sugano, Eriko, Allen, Annette E., Lawrence, Jean M., Tomita, Hiroshi, Coffey, Peter J., Vugler, Anthony A.
Publicado em 2010

Array-based Discovery of Aptamer Pairs

Por Cho, Minseon, Oh, Seung Soo, Nie, Jeff, Stewart, Ron, Radeke, Monte J., Eisenstein, Michael, Coffey, Peter J., Thomson, James A., Soh, H. Tom
Publicado no Anal Chem (2014)

Cone photoreceptor definition on adaptive optics retinal imaging

Por Muthiah, Manickam Nick, Gias, Carlos, Chen, Fred Kuanfu, Zhong, Joe, McClelland, Zoe, Sallo, Ferenc B, Peto, Tunde, Coffey, Peter J, da Cruz, Lyndon
Publicado em 2014

Nonsense-mediated mRNA decay efficiency varies in choroideremia providing a target to boost small molecule therapeutics

Por Sarkar, Hajrah, Mitsios, Andreas, Smart, Matthew, Skinner, Jane, Welch, Ailsa A, Kalatzis, Vasiliki, Coffey, Peter J, Dubis, Adam M, Webster, Andrew R, Moosajee, Mariya
Publicado no Hum Mol Genet (2019)

Melanopsin Contributions to Irradiance Coding in the Thalamo-Cortical Visual System

Por Brown, Timothy M., Gias, Carlos, Hatori, Megumi, Keding, Sheena R., Semo, Ma'ayan, Coffey, Peter J., Gigg, John, Piggins, Hugh D., Panda, Satchidananda, Lucas, Robert J.
Publicado em 2010

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins

Por Schwarz, Nele, Lane, Amelia, Jovanovic, Katarina, Parfitt, David A., Aguila, Monica, Thompson, Clare L., da Cruz, Lyndon, Coffey, Peter J., Chapple, J. Paul, Hardcastle, Alison J., Cheetham, Michael E.
Publicado no Hum Mol Genet (2017)

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins

Por Schwarz, Nele, Lane, Amelia, Jovanovic, Katarina, Parfitt, David A., Aguila, Monica, Thompson, Clare L., da Cruz, Lyndon, Coffey, Peter J., Chapple, J. Paul, Hardcastle, Alison J., Cheetham, Michael E.
Publicado no Hum Mol Genet (2017)

Vascular changes in diabetic retinopathy – A longitudinal study in the Nile rat

Por Toh, Huishi, Smolentsev, Alexander, Bozadjian, Rachel V., Keeley, Patrick W., Lockwood, Madison D., Sadjadi, Ryan, Clegg, Dennis O., Blodi, Barbara A., Coffey, Peter J., Reese, Benjamin E., Thomson, James A.
Publicado no Lab Invest (2019)

Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay

Por Carr, Amanda-Jayne, Vugler, Anthony, Lawrence, Jean, Li Chen, Li, Ahmado, Ahmed, Chen, Fred K., Semo, Ma’ayan, Gias, Carlos, da Cruz, Lyndon, Moore, Harry D., Walsh, James, Coffey, Peter J.
Publicado em 2009

Hsp90 inhibition protects against inherited retinal degeneration

Por Aguilà, Mònica, Bevilacqua, Dalila, McCulley, Caroline, Schwarz, Nele, Athanasiou, Dimitra, Kanuga, Naheed, Novoselov, Sergey S., Lange, Clemens A.K., Ali, Robin R., Bainbridge, James W., Gias, Carlos, Coffey, Peter J., Garriga, Pere, Cheetham, Michael E.
Publicado em 2014

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells

Por Schwarz, Nele, Carr, Amanda-Jayne, Lane, Amelia, Moeller, Fabian, Chen, Li Li, Aguilà, Mònica, Nommiste, Britta, Muthiah, Manickam N., Kanuga, Naheed, Wolfrum, Uwe, Nagel-Wolfrum, Kerstin, da Cruz, Lyndon, Coffey, Peter J., Cheetham, Michael E., Hardcastle, Alison J.
Publicado no Hum Mol Genet (2015)

Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs

Por Ramsden, Conor M., Nommiste, Britta, R. Lane, Amelia, Carr, Amanda-Jayne F., Powner, Michael B., J. K. Smart, Matthew, Chen, Li Li, Muthiah, Manickam N., Webster, Andrew R., Moore, Anthony T., Cheetham, Michael E., da Cruz, Lyndon, Coffey, Peter J.
Publicado no Sci Rep (2017)

Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction

Por Coffey, Peter J., Gias, Carlos, McDermott, Caroline J., Lundh, Peter, Pickering, Matthew C., Sethi, Charanjit, Bird, Alan, Fitzke, Fred W., Maass, Annelie, Chen, Li Li, Holder, Graham E., Luthert, Philip J., Salt, Thomas E., Moss, Stephen E., Greenwood, John
Publicado em 2007

Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups

Por Parfitt, David A., Lane, Amelia, Ramsden, Conor M., Carr, Amanda-Jayne F., Munro, Peter M., Jovanovic, Katarina, Schwarz, Nele, Kanuga, Naheed, Muthiah, Manickam N., Hull, Sarah, Gallo, Jean-Marc, da Cruz, Lyndon, Moore, Anthony T., Hardcastle, Alison J., Coffey, Peter J., Cheetham, Michael E.
Publicado no Cell Stem Cell (2016)