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Using induced pluripotent stems cells to understand retinal ciliopathy disease mechanisms and develop therapies
The photoreceptor cells in the retina have a highly specialized sensory cilium, the outer segment, which is important for detecting light. Mutations in cilia related genes often result in retinal degeneration. The ability to reprogram human cells into induced pluripotent stem cells (iPSCs) and then...
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| Publicado no: | Biochem Soc Trans |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238943/ https://ncbi.nlm.nih.gov/pubmed/27911706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160156 |
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